Improvement by Satureja khuzestanica essential oil of malathion-induced red blood cells acetylcholinesterase inhibition and altered hepatic mitochondrial glycogen phosphorylase and phosphoenolpyruvate carboxykinase activities

Basiri, Soha; Esmaily, Hadi; Vosough-Ghanbari, Sanaz; Mohammadirad, Azadeh; Yasa, N; Abdollahi, Mohammad

doi:10.1016/j.pestbp.2007.04.006

Cited by 44 publications

(32 citation statements)

References 35 publications

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“…AChE inhibitory activity of S. khuzestanica was also tested by Basiri et al (2007). In this study, the protective effect of this sample on toxicity of Malathion, a commonly used organophosphorus (OP), was investigated.…”

Section: Acetylcholinesterase (Ache) and Butyrylcholinesterase (Bche)mentioning

confidence: 99%

A pharmacological and phytochemical overview onSatureja

Tepe

Çilkiz

2015

Pharmaceutical Biology

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Context: Satureja (Lamiaceae) species are used as flavoring compounds in food, pharmaceutical, and cosmetic industries because of its sweetness and simple cultivation characteristics. They have traditionally been used as muscle pain relievers, tonic, and carminative agents to treat stomach and intestinal disorders such as cramps, nausea, indigestion, and diarrhea, due to their considerable phytochemical characteristics. Objective: This review evaluates some information published since 1989 on Satureja genus from a systematic perspective in terms of its pharmacological and phytochemical characteristics. Materials and methods: Web of Science, PubMed, Scopus, and Google Scholar databases were searched up to March 2014. ''Satureja'' was used as a research term without narrowing or limiting research elements. After obtaining all reports from database (a total number is about 637), the papers were carefully analyzed in order to find data related to the topic of this review. Results: In this review, 453 reports were used which were published between 1989 and 2014. The study was compiled into two sections (Pharmacology and Phytochemistry). In the pharmacology section, more than 50 different activities were studied. In the second section, in addition to other compounds and inorganic substances, volatiles, phenolic acids, and flavonoids were discussed. Discussion and conclusion: According to our contemporary information, Satureja species have been evaluated for their wide range of biological activities. However, a small part of these studies have been carried out on the active principles. Therefore, in the future, more studies should be carried out to identify responsible phytochemicals for the various activities.

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Section: Acetylcholinesterase (Ache) and Butyrylcholinesterase (Bche)mentioning

confidence: 99%

A pharmacological and phytochemical overview onSatureja

Tepe

Çilkiz

2015

Pharmaceutical Biology

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“…68 Reactive oxygen species lead to the upregulation of PEPCK gene expression via stress-activated signaling pathways. 47,69 In their in vivo study, Basiri et al 48 investigated improvement affected by S. khuzestanica essential oil in the malathion-induced alteration of hepatic mitochondrial glycogen phosphorylase and PEPCK activities in rats. S. khuzestanica essential oil facilitated recovery from hyperglycemia and helped restore PEPCK and glycogen phosphorylase activity.…”

Section: Results and Discussion Efficacymentioning

confidence: 99%

A Review of the Benefits of Satureja Species on Metabolic Syndrome and Their Possible Mechanisms of Action

Babajafari

Nikaein

Mazloomi

et al. 2015

J Evid Based Complementary Altern Med

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Metabolic syndrome, also known as insulin resistance disorder, is the simultaneous manifestation of multiple metabolic disorders in an individual. The present-day complementary and alternative therapies suggest several medicinal herbs that may have the potential to improve one or multiple complications of metabolic syndrome. All of them have their own limitations in efficacy and unwanted effects. Therefore, we reviewed species of Satureja as widespread medicinal herbs and potentially good remedies for metabolic syndrome. We reviewed literature found in PubMed and the ISI Web of Knowledge with the key word Satureja in the title. The influence of any species of Satureja on any disease or syndrome, enzymatic, metabolic, or physiological pathways, in human, animals, or in vitro conditions related to any characteristics of metabolic syndrome were considered. The main outcomes of treatment with Satureja species were categorized, and the possible mechanisms of action are discussed in this article.

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“…The levels of ROS and RNS are balanced by two lines of cell defense including the enzymatic (as the first line) and nonenzymatic (as the second line) antioxidants providing maximal protection against OTS via ROS clearing and scavenging (88). Preventive and therapeutic features of antioxidants are well-known and they have been known to have a critical role in protecting biological sites from oxidative injuries (89)(90)(91)(92). By now, many kinds of fruits, vegetables, plant food materials, and dietary supplementation have been investigated for their antioxidant capabilities (92)(93)(94).…”

Section: Antioxidantsmentioning

confidence: 99%

“…Preventive and therapeutic features of antioxidants are well-known and they have been known to have a critical role in protecting biological sites from oxidative injuries (89)(90)(91)(92). By now, many kinds of fruits, vegetables, plant food materials, and dietary supplementation have been investigated for their antioxidant capabilities (92)(93)(94). The association between specific oxidative damage and sites of injury in many different types of neurodegeneration conditions are not clear exactly.…”

Section: Antioxidantsmentioning

confidence: 99%

Neurological Disorders and Oxidative Toxic Stress: A Role of Metal Nanoparticles

Mazdeh

Rahiminejad

Nili‐Ahmadabadi

et al. 2016

Jundishapur J Nat Pharm Prod

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Context: Oxidative stress is a hallmark of many types of neuropathology disorders and underlying mechanism in several neurodegenerative diseases and brain injuries. The CNS is particularly susceptible to oxidative toxic stress (OTS). Reactive oxygen spices are the basic inflammation and neurotoxicity mediators in ischemia/reperfusion injuries. The purpose of the present review is to provide an overview of some nanoparticles (NPs) in developing OTS conditions and neurological disorders. Evidence Acquisition: Here, a nanotechnology approach is evaluated using NPs in human neuronal protection against OTS. It may be wide therapeutic applications in the case of acute and/or chronic neurodegenerative disorders related to OTS. Results: In the brain of mice treated with nanosize TiO 2 , a significant association was found between the ability to induce the production of ROS and metabolic stress in intracellular environments and inflammatory responses in mice brai. The large surface area of AgNPs may efficiently facilitate the radicals generation including ROS in various organs. The production of ROS may cause DNA damage, cellular apoptosis, and activation of the mitogen activated protein kinase (MAPK) pathways which is responsible for regulating many cellular processes. Prolonged and excessive OTS may contribute to the activation of transcription factors and genes responsible for inflammation responses such as NF-κB and AP-1. Furthermore, OTS may contribute to the onset of neurodegenerative diseases. The ability of CuONPs to generate OTS in vitro studies has been demonstrated; however, information on the neurotoxicity of the CuONPs in vivo is low. Conclusions:The NPs-induced OTS may increase the pro-inflammatory responses. On the other hand, administration of antioxidants such as NAC and vitamin C and E prior to exposure to metal NPs significantly decreases OTS conditions.

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Improvement by Satureja khuzestanica essential oil of malathion-induced red blood cells acetylcholinesterase inhibition and altered hepatic mitochondrial glycogen phosphorylase and phosphoenolpyruvate carboxykinase activities

Cited by 44 publications

References 35 publications

A pharmacological and phytochemical overview onSatureja

A pharmacological and phytochemical overview onSatureja

A Review of the Benefits of Satureja Species on Metabolic Syndrome and Their Possible Mechanisms of Action

Neurological Disorders and Oxidative Toxic Stress: A Role of Metal Nanoparticles

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