“…In Uvira, a city in eastern DRC affected by protracted conflict, population displacement, and flooding, cholera is endemic, and stable transmission is punctuated by seasonal outbreaks ( 8 ). Citywide interventions include an ongoing piped water supply program with household tap installation beginning in late 2019 ( 9 ) and mass vaccination in mid-2020 ( 10 ). Using an enhanced surveillance system with rapid diagnostic testing (RDT), we investigated the location, timing, and prediction of clusters to identify outbreaks earlier and trigger early response.…”