Improved sensitivity of MRI in multiple sclerosis by use of extensive standardized procedures

Vyver, F L Van de; Truyen, Luc; Gheuens, J.; Degryse, H; Peersman, Greet V.; Martin, Jean‐Jacques

doi:10.1016/0730-725x(89)90547-x

Cited by 11 publications

(1 citation statement)

References 26 publications

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“…Since this would bias the analysis, strict criteria for the identification of MS lesions were used in this study, and this may have biased the chosen MS lesions to be larger as well as peri ventricular plaque. Furthermore, any lesion that did not meet the previously described criteria on MRI [14] was not included as an MS plaque. A total of 58 larger MS lesions were used in the statistical analysis.…”

Section: Resultsmentioning

confidence: 99%

Magnetic Resonance Imaging Characteristics of Multiple Sclerosis Plaques Imaged with Two‐dimensional and Three‐dimensional Fourier Transform Techniques at Low and Mid Field Strengths

Rothschild¹,

Kramer

Schulz³

et al. 1991

Journal of Neuroimaging

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A total of 58 multiple sclerosis lesions from 16 patients were used to characterize the performance of a low field system for the detection of edematous (e.g., water-elevating) brain lesions. Contrast, signal-to-noise, and their product (signal difference to noise) were measured for two-dimensional and three-dimensional Fourier transform techniques at low field strength (640 G) and compared to two-dimensional sequences at mid field strength (3,500 G). The results showed numerically that low-field strength magnetic resonance imaging can reliably detect multiple sclerosis lesions, and, by extension, other water-elevating lesions, although with lower confidence levels.

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Section: Resultsmentioning

confidence: 99%

Magnetic Resonance Imaging Characteristics of Multiple Sclerosis Plaques Imaged with Two‐dimensional and Three‐dimensional Fourier Transform Techniques at Low and Mid Field Strengths

Rothschild¹,

Kramer

Schulz³

et al. 1991

Journal of Neuroimaging

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Brain Magnetic Resonance Imaging in Acute Optic Neuritis

Beck¹

1993

Arch Neurol

107

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Quantitative MRI studies for assessment of multiple sclerosis

Pannizzo

Stallmeyer

Friedman

et al. 1992

Magnetic Resonance in Med

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Although magnetic resonance imaging (MRI) is a valuable aid in the initial diagnosis of multiple sclerosis (MS), quantitatively MRI has been disappointing in staging and evaluating therapy protocols by means of serial examinations. In this study, image processing algorithms were developed for the global analysis of MR images of the cerebrum. Limited three-dimensional segmentation was achieved through histogram analysis by these algorithms, which are essentially operator independent. The effects of coil response and tip angles, patient positioning, and interslice gap thicknesses were examined for 10 MS patients with repeated examinations for a total of 72 images. Effects of technique and instrumentation errors were approximately 6%, and agreement between two independent operators for measuring the total MR pixel sum from periventricular effusions and intense MS plaques was better than 97% with a standard deviation of 2.9%.

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Improved sensitivity of MRI in multiple sclerosis by use of extensive standardized procedures

Cited by 11 publications

References 26 publications

Magnetic Resonance Imaging Characteristics of Multiple Sclerosis Plaques Imaged with Two‐dimensional and Three‐dimensional Fourier Transform Techniques at Low and Mid Field Strengths

Magnetic Resonance Imaging Characteristics of Multiple Sclerosis Plaques Imaged with Two‐dimensional and Three‐dimensional Fourier Transform Techniques at Low and Mid Field Strengths

Brain Magnetic Resonance Imaging in Acute Optic Neuritis

Quantitative MRI studies for assessment of multiple sclerosis

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