Improved self-assembled thiol stationary phases in microfluidic gas separation columns

Shakeel, Hamza; Wang, Dong; Heflin, James R.; Agah, Masoud

doi:10.1016/j.snb.2015.03.107

Cited by 24 publications

(9 citation statements)

References 45 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Similarly, due to very narrow channel dimensions, other thin film coating techniques developed by our group (LbL self-assembly of SNPs [22] and gold thiol-based stationary phases [53,54]) could not be used for HDSPCs. Therefore, the use of high-yield ALDsilane based method not only presents an easy route towards the development of separation columns with very narrow channels (even smaller than 5 µm) but also provides a wafer level and semiconductor process compatible technique for the realization an integrated µGC chip [24,26].…”

Section: Resultsmentioning

confidence: 99%

High density semipacked separation columns with optimized atomic layer deposited phases

Shakeel

Agah

2017

Sensors and Actuators B: Chemical

Self Cite

View full text Add to dashboard Cite

This paper reports the development of a new class of high-performance microfabricated separation columns called high-density semi-packed columns (HDSPCs). These columns are realized by using a meter long and 145 µm-wide silicon microchannel design with embedded circular micropillars (15 µm diameters) and 5 µm post spacing (perpendicular to the gas flow). The HDSPCs are coated using our previously developed atomic layer deposition (ALD) based aluminium oxide and silane functionalized thin adsorben t film. Moreover, in this study we optimize both ALD deposition temperature (100 ° C, 150 °C, 250 ° C and 300 ° C) and film thickness (10 nm, 20 nm and 30 nm) using different chromatographic parameters (plate number, peak-to-peak resolution, and separation factor). Additionally, the thermodynamic characteristics of these silane functionalized/ALD films are also studied using Van't Hoff plots. These columns with optimized stationary phases are able to provide ≈8,000 effective plates/meter and

show abstract

Section: Resultsmentioning

confidence: 99%

High density semipacked separation columns with optimized atomic layer deposited phases

Shakeel

Agah

2017

Sensors and Actuators B: Chemical

Self Cite

View full text Add to dashboard Cite

show abstract

“…The separation efficiency of these columns is, however, not as high as that observed with a dynamically coated microcolumn. 62,115 Two promising classes of materials that have recently attracted much attention as stationary phases in microfabricated columns are metal−organic frameworks (MOFs) 124 and room temperature ionic liquids (RTILs). 47,103,115 MOFs are porous crystalline materials formed by coordination of metal cations and multidentate organic ligands.…”

Section: Analytical Chemistrymentioning

confidence: 99%

“…Nonetheless, in the case of high-aspect-ratio rectangular columns, the efficiency can be increased by decreasing the width of the channel, and the sample capacity (maximum amount of sample that can injected washout overloading) and flow rate can be increased by increasing the height, thereby offering a possibility of getting better efficiencies compared to conventional capillary columns . Considerable efforts are being made to increase the separation efficiency of the columns by exploring different column architectures ,,− and stationary phase coating techniques. ,− …”

Section: Separation Columnsmentioning

confidence: 99%

Micro Gas Chromatography: An Overview of Critical Components and Their Integration

2018

Self Cite

View full text Add to dashboard Cite

Among a number of gas analyzers, portable gas chromatography (GC) systems created by the integration of microfabricated components are promising candidates for rapid and on-site analysis of a number of complex chemical mixtures. This Feature provides a snapshot of the progress made in developing micro gas chromatography (μGC) systems in the last 4 decades. In particular, we discuss the development of microfabricated preconcentrators, separation columns, and detectors. Furthermore, we review different stationary phase materials used to coat the separation columns and the major efforts toward the development of an integrated μGC.

show abstract

“…have poor anti-interference ability and low resolution, which were very limited for on-site analysis, GC columns with strong separation capability were widely integrated into portable instruments. As the MEMS technology developed, instead of the conventional columns, micro GC columns (Lambertus et al, 2005;Reidy et al, 2006;Lobinski et al, 1999;Ali et al, 2009;Haudebourg et al, 2012;Sun et al, 2013aSun et al, , 2013bShakeel et al, 2015) with advantages of rapid analysis, portability, small size and less power consumption have become the most widely used tool for separating gas mixtures, resolving the bottleneck problem of interference. Lobinski et al (1999) reported a multicapillary column with high efficiency.…”

Section: Introductionmentioning

confidence: 99%

Mini pretreatment system integrated with micro pre-concentrator and micro GC column

Zhang

Sun

Zhu

et al. 2017

View full text Add to dashboard Cite

Purpose As the concentration of environmental samples was generally very low and existing analytical instruments had limited sensitivity, developing mini pre-treatment systems for effectively concentrating the components was very important and necessary. The purposed of this paper is to develop mini pretreatment system integrated with micro pre-concentrator and micro GC column. Design/methodology/approach In this work, a mini pre-treatment system integrated with a micro pre-concentrator and a micro gas chromatograph (GC) column was proposed. The micro pre-concentrator filled with single-walled carbon nanotubes as adsorbent materials was able to effectively concentrate the trace environmental sample, which dramatically improved the response of detectors. In addition, instead of conventional columns, micro GC columns were able to effectively separate gas mixtures, which are able to overcome low resolution and poor anti-interference ability of portable instruments. Findings The results demonstrated that the proposed pre-treatment system was able to concentrate the trace sample with a concentration factor of 15 and effectively separate the gas mixtures with a resolution over 1.5. Originality/value A mini pre-treatment system integrated with a micro pre-concentrator and a micro GC column was proposed.

show abstract

Improved self-assembled thiol stationary phases in microfluidic gas separation columns

Cited by 24 publications

References 45 publications

High density semipacked separation columns with optimized atomic layer deposited phases

High density semipacked separation columns with optimized atomic layer deposited phases

Micro Gas Chromatography: An Overview of Critical Components and Their Integration

Mini pretreatment system integrated with micro pre-concentrator and micro GC column

Contact Info

Product

Resources

About