Improved Results after Repair of Complete Atrioventricular Septal Defect

Ono, Masamichi; Goerler, Heidi; Boethig, Dietmar; Bertram, Harald; Westhoff-Bleck, Mechthild; Haverich, Axel; Breymann, Thomas

doi:10.1111/j.1540-8191.2009.00912.x

Cited by 9 publications

(6 citation statements)

References 20 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Patients with DS are considered to be at higher risk for pulmonary hypertension probably because of a diminished number of alveoli, a thinner media of pulmonary arterioles, and an impaired endothelial function 6 . Early corrective cardiac surgeries are necessary to prevent irreversible pulmonary‐vascular damage 7 …”

Section: Cardiovascular Abnormalitiesmentioning

confidence: 99%

“…6 Early corrective cardiac surgeries are necessary to prevent irreversible pulmonary-vascular damage. 7 For patients presenting with unrepaired cyanotic congenital heart defects, prosthetic valves, or previous episodes of infective endocarditis (IE), as well as for recipients of cardiac transplantation who develop cardiac valvulopathy, the American Heart Association (AHA) 8 recommends the use of antibiotic prophylaxis ( Table 2) before dental procedures, which could cause transient bacteremias. According to the most recent AHA guidelines, 8 such procedures are those which involve manipulation of gingival tissue or the periapical region and perforation of the oral mucosa, such as during subgingival scaling, dental extractions, suture removal, rubber dam matrix placement, and placing of orthodontic bands.…”

Section: E D I C a L P R O B L E M S O F P A T I E N T S W I T H D mentioning

confidence: 99%

See 1 more Smart Citation

Medical problems and oral care of patients with Down syndrome: a literature review

Abanto¹,

Ciamponi²,

Francischini³

et al. 2011

Special Care in Dentistry

View full text Add to dashboard Cite

show abstract

Section: Cardiovascular Abnormalitiesmentioning

confidence: 99%

Section: E D I C a L P R O B L E M S O F P A T I E N T S W I T H D mentioning

confidence: 99%

Medical problems and oral care of patients with Down syndrome: a literature review

Abanto¹,

Ciamponi²,

Francischini³

et al. 2011

Special Care in Dentistry

View full text Add to dashboard Cite

show abstract

“…Despite improvement in patient mortality, surgery has had a limited effect on the LAVVR after surgery in the last few years.Despite complete cleft closure, the prevalence of LVAVR is almost constant [13,34,35]. In North America and Europe, 9%-17% of patients with AVSD have significant left atrioventricular septal defect despite surgical repair [14,26].…”

Section: Discussionmentioning

confidence: 99%

“…Furthermore, the amount of residual defects such as mitral valve, shunt, and heart block failure were high [11]. However, improvements in precise preoperative diagnosis, better understanding of surgical anatomy, progression in surgical technique, protection and post-operative care (including treatment of pulmonary pressure events) contribute to increased survival rates and decreasing re-surgical intervention [12][13][14][15][16][17][18].…”

Section: Issn 0970-938x Wwwbiomedresinfomentioning

confidence: 99%

“…This impairment not only increases the risk of "reoperation", but also can increase the mortality rate and even the cost of hospitalization, by hemodynamic impairment [14,[27][28][29]. In addition, AVSD reveals a wide range of heart and non-cardiac diseases, so it requires careful preoperative examination and multiple surgical procedures with different treatment options.…”

Section: Issn 0970-938x Wwwbiomedresinfomentioning

confidence: 99%

See 1 more Smart Citation

Surgical outcome of atrioventricular septal defect: A 10 years review

Omrani¹,

Hashemzadeh²

2018

biomedicalresearch

View full text Add to dashboard Cite

Background: Surgical management of patients with Atrioventricular Septal Defect (AVSD) has advanced over the last decades. The aims of this study were to evaluate the early and late outcomes in patients undergoing operation at a single heart center. Methods: Between April 2006 and April 2016, 337 consecutive patients underwent Atrioventricular Septal Defect (AVSD) repair at the Shaheed Rajaie Heart Center. The patients were subtyped as 73 (21.7%) partial, 67 (19.9%) transitional and 197 (58.5%) complete. Results: At the time of preoperative evaluation, there were 39 cases (11.7%) with moderate to severe or severe Left Atrioventricular Valve Regurgitation (LAVVR). Previous Pulmonary Artery banding (PA banding) had been performed in 144 (42.7%) patients and associated malformations were found in 115 (34.1%). Type of surgical repair was single patch 193 (57.3%), double patch 144 (42.7%), and single atrial septal defect patch with primary ventricular septal defect closure in TAVSD 64 (95.5%). 141 patients (71.6%) with CAVSD underwent definitive early repair by using a two patch technique and complete cleft closure. Annuloplasty and/or commissuroplasty were performed for 60 (17.8%) patients and debanding was also implemented in all patients. Mean hours for ventilation were determined as 26.8 ± 2.8. Mean days for intensive care unit was defined to be 4.4 ± 0.2, and total hospitalization time was as 26.8 ± 0.5. A 1 month, 21.9% (72 of 328) had ejection fraction less than 55%; 33 (10.9%) had more than moderate LAVVR; 73 (24.2%) had residual Ventricular Septal Defect (VSD), followed by 14 cases (4.6%) with residual Atrial Septal Defect (ASD) and 2 cases (0.6%) with Left Ventricular Outlet Tract Obstruction (LVOTO). Conclusions: Definitive early repair for AVSD can be performed with acceptable results. Despite a complete cleft closure, LAVVR remains the most common residual defect that more frequently required reoperation in the future.

show abstract

Contemporary outcomes of complete atrioventricular septal defect repair: Analysis of the Society of Thoracic Surgeons Congenital Heart Surgery Database

Louis

Jodhka

Jacobs³

et al. 2014

The Journal of Thoracic and Cardiovascular Surgery

View full text Add to dashboard Cite

Objective Contemporary outcomes data for complete atrioventricular septal defect (CAVSD) repair are limited. We sought to describe early outcomes of CAVSD repair across a large multicenter cohort, and explore potential associations with patient characteristics, including age, weight, and genetic syndromes. Methods Patients in the Society of Thoracic Surgeons Congenital Heart Surgery Database having repair of CAVSD (2008–2011) were included. Preoperative, operative, and outcomes data were described. Univariate associations between patient factors and outcomes were described. Results Of 2399 patients (101 centers), 78.4% had Down syndrome. Median age at surgery was 4.6 months (interquartile range, 3.5–6.1 months), with 11.8% (n = 284) aged ≤2.5 months. Median weight at surgery was 5.0 kg (interquartile range, 4.3–5.8 kg) with 6.3% (n = 151) <3.5 kg. Pulmonary artery band removal at CAVSD repair was performed in 122 patients (4.6%). Major complications occurred in 9.8%, including permanent pacemaker implantation in 2.7%. Median postoperative length of stay (PLOS) was 8 days (interquartile range, 5–14 days). Overall hospital mortality was 3.0%. Weight<3.5 kg and age ≤ 2.5 months were associated with higher mortality, longer PLOS, and increased frequency of major complications. Patients with Down syndrome had lower rates of mortality and morbidities than other patients; PLOS was similar. Conclusions In a contemporary multicenter cohort, most patients with CAVSD have repair early in the first year of life. Prior pulmonary artery band is rare. Hospital mortality is generally low, although patients at extremes of low weight and younger age have worse outcomes. Mortality and major complication rates are lower in patients with Down syndrome.

show abstract

Improved Results after Repair of Complete Atrioventricular Septal Defect

Cited by 9 publications

References 20 publications

Medical problems and oral care of patients with Down syndrome: a literature review

Medical problems and oral care of patients with Down syndrome: a literature review

Surgical outcome of atrioventricular septal defect: A 10 years review

Contemporary outcomes of complete atrioventricular septal defect repair: Analysis of the Society of Thoracic Surgeons Congenital Heart Surgery Database

Contact Info

Product

Resources

About