Improved reliability of the NIH Stroke Scale using video training. NINDS TPA Stroke Study Group.

Lyden, Patrick D.; Brott, Thomas G.; Tilley, Barbara C.; Welch, K. M. A.; Mascha, Edward J.; Levine, Steven R.; Haley, E. Clarke; Grotta, James C.; Marler, John R.

doi:10.1161/01.str.25.11.2220

Cited by 1,072 publications

(728 citation statements)

References 23 publications

(10 reference statements)

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“…25 Diabetes was defined on the basis of prior diagnosis, use of hypoglycemic agents/insulin or as defined by World Health Organization criteria. 26 The admission National Institutes of Health Stroke Scale score 27 was recorded. Stroke was subtyped using a pragmatic modification of the Trial of Org 10172 in Acute Stroke Treatment (TOAST) classification used in the Greater Metropolitan Clinical Taskforce for Stroke in New South Wales, Australia.…”

Section: Study Populationmentioning

confidence: 99%

The relationship between aortic stiffness and changes in retinal microvessels among Asian ischemic stroke patients

et al. 2011

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Large-artery stiffness is a risk factor for stroke, including cerebral small-vessel disease. Retinal microvascular changes are thought to mirror those in cerebral microvessels. We investigated the relationship between aortic stiffness and retinal microvascular changes in Asian ischemic stroke patients. We studied 145 acute ischemic stroke patients in Singapore who had aortic stiffness measurements using carotid-femoral pulse wave velocity (cPWV). Retinal photographs were assessed for retinal microvessel caliber and qualitative signs of focal arteriolar narrowing, arteriovenous nicking and enhanced arteriolar light reflex. Aortic stiffening was associated with retinal arteriolar changes. Retinal arteriolar caliber decreased with increasing cPWV (r ¼ À0.207, P ¼ 0.014).After adjusting for age, gender, hypertension, diabetes, mean arterial pressure and small-vessel stroke subtype, patients within the highest cPWV quartile were more likely to have generalized retinal arteriolar narrowing defined as lowest caliber tertile (odds ratio (OR) 6.84, 95% confidence interval (CI) 1.45-32.30), focal arteriolar narrowing (OR 13.85,), arteriovenous nicking (OR 5.08, CI 1.12-23.00) and enhanced arteriolar light reflex (OR 3.83,), compared with those within the lowest quartile. In ischemic stroke patients, aortic stiffening is associated with retinal arteriolar luminal narrowing as well as features of retinal arteriolosclerosis.

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Section: Study Populationmentioning

confidence: 99%

The relationship between aortic stiffness and changes in retinal microvessels among Asian ischemic stroke patients

et al. 2011

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“…We used a retrospective NIHSS [32][33] to assess stroke severity [34]. The elements to complete the retrospective NIHSS can be found in most medical charts.…”

Section: Stroke Severitymentioning

confidence: 99%

Prevalence, predictors, and outcomes of poststroke falls in acute hospital setting

Schmid¹,

Wells²,

Concato³

et al. 2010

JRRD

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Abstract-Falls are a serious medical complication following stroke. The objectives of this study were to (1) confirm the prevalence of falls among patients with stroke during acute hospitalization, (2) identify factors associated with falls during the acute stay, and (3) examine whether in-hospital falls were associated with loss of function after stroke (new dependence at discharge). We completed a secondary analysis of data from a retrospective cohort study of patients with ischemic stroke who were hospitalized at one of four hospitals. We used logistic regression to identify factors associated with inpatient falls and examine the association between falls and loss of function. Among 1,269 patients with stroke, 65 (5%) fell during the acute hospitalization period. We found two characteristics independently associated with falls: greater stroke severity (National Institutes of Health Stroke Scale [NIHSS] 8, adjusted odds ratio [OR] = 3.63, 95% confidence interval [CI]: 1.46-9.00) and history of anxiety (adjusted OR = 4.90, 95% CI: 1.70-13.90). Falls were independently associated with a loss of function (adjusted OR = 9.85, 95% CI: 1.22-79.75) even after adjusting for age, stroke severity, gait abnormalities, and past stroke. Stroke severity (NIHSS 8) may be clinically useful during the acute inpatient setting in identifying those at greatest risk of falling. Given the association between falls and poor patient outcomes, rehabilitation interventions should be implemented to prevent falls poststroke.Abbreviations: ADL = activity of daily living, CI = confidence interval, IADL = instrumental activity of daily living, NIHSS = National Institutes of Health Stroke Scale, OR = odds ratio, SD = standard deviation, TIA = transient ischemic attack, UTI = urinary tract infection, VA = Department of Veterans Affairs.

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“…4 It is a reliable tool that physicians and even nonphysicians can use to assess the clinical status of patients with stroke. 5 Because the NIHSS examination takes fewer than 8 minutes to administer, has good interrater reliability with proper training, [6][7][8][9] and is a valid prognostic indicator, its clinical application has expanded to quantify deteriorating neurologic status. 2 Neurologic deterioration (ND), an event that occurs in about one-third of patients with acute ischemic stroke (AIS) and contributes to morbidity and mortality, 10,11 has no standardized definition.…”

Section: Introductionmentioning

confidence: 99%

What Change in the National Institutes of Health Stroke Scale Should Define Neurologic Deterioration in Acute Ischemic Stroke?

Siegler

Boehme

Kumar

et al. 2013

Journal of Stroke and Cerebrovascular Diseases

103

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Improved reliability of the NIH Stroke Scale using video training. NINDS TPA Stroke Study Group.

Cited by 1,072 publications

References 23 publications

The relationship between aortic stiffness and changes in retinal microvessels among Asian ischemic stroke patients

The relationship between aortic stiffness and changes in retinal microvessels among Asian ischemic stroke patients

Prevalence, predictors, and outcomes of poststroke falls in acute hospital setting

What Change in the National Institutes of Health Stroke Scale Should Define Neurologic Deterioration in Acute Ischemic Stroke?

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