Improved reconstruction of crossing fibers in the mouse optic pathways with orientation distribution function fingerprinting
Patryk Filipiak,
Thajunnisa A. Sajitha,
Timothy M. Shepherd
et al.
Abstract:PurposeThe accuracy of diffusion MRI tractography reconstruction decreases in the white matter regions with crossing fibers. The optic pathways in rodents provide a challenging structure to test new diffusion tractography approaches because of the small crossing volume within the optic chiasm and the unbalanced 9:1 proportion between the contra‐ and ipsilateral neural projections from the retina to the lateral geniculate nucleus, respectively.MethodsCommon approaches based on Orientation Distribution Function … Show more
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