Improved polarization contrast method for surface plasmon resonance imaging sensors by inert background gold film extinction

Dong, Wei; Pang, Kai; Luo, Qiaohui; Huang, Zihao; Wang, Xiaoping; Tong, Limin

doi:10.1016/j.optcom.2015.01.063

Cited by 11 publications

(4 citation statements)

References 18 publications

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“…The first step in data processing of the SPR sensor is to remove the high-frequency system noise introduced by the CCD sampling using the empirical mode decomposition (EMD) of the Hilbert-Huang transform (HHT) algorithm [35,36]. To achieve this, the SPR monitoring curve was first decomposed into the sum of a limited number of intrinsic mode functions (IMFs).…”

Section: Signal Processing Of the Sensormentioning

confidence: 99%

High-performance polarization control modulated surface plasmon resonance sensor based on monolayer graphene/Au-NPs architecture for detection of DNA hybridization

Sun

Cai

Qiao

et al. 2019

Meas. Sci. Technol.

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A highly sensitive polarization control modulated plasmonic biosensor based on monolayer graphene/Au-NPs for direct detection of single-stranded DNA (ssDNA) hybridization is reported. The presence of monolayer graphene on gold film provides novel functionalized derivatives through π-stacking interactions. In addition, the online assembly strategy via in situ monitoring between ssDNA and Au-NPs makes the binding easier and quantifiable. The use of strong plasmon-mediated energy confinements induces an approximately 30-fold intense field enhancement of the reflected light. The architecture exhibits a linear dynamic range of 10−15 to 10−7 M for the detection of target ssDNA. Moreover, the new biosensor can achieve an ultralow detection limit of 500 aM for 23-mer ssDNA via improved sensitivity to molecular bindings.

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Section: Signal Processing Of the Sensormentioning

confidence: 99%

High-performance polarization control modulated surface plasmon resonance sensor based on monolayer graphene/Au-NPs architecture for detection of DNA hybridization

Sun

Cai

Qiao

et al. 2019

Meas. Sci. Technol.

Self Cite

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“…After observing the nano-structure of FlexBrite from the SEM image in figures 1(e)-(j) we understand that the polymer nano-pillars are covered with large hemi-ellipsoidal gold on top and many close-packed small gold nano-particles on the side wall. To explain the SERS enhancement from these structures, we believe that the LSPR effect comes from the nano-particles on the side wall of each single nanopillar while the periodic structure of the nano-pillars contributed to the SPR enhancement [15,[33][34][35][36][37][38]. After we sputtered thicker SiO 2 before coating gold, the spacing between adjacent pillars became smaller.…”

Section: Fdtd Modeling and Simulationmentioning

confidence: 99%

Large-area, lithography-free, low-cost SERS sensor with good flexibility and high performance

Jiang

Ameen

et al. 2016

Nanotechnology

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Cost-effective, sensitive and bio-compatible surface-enhanced Raman spectroscopy (SERS) substrate has been in high demand since the Raman spectrum was designated as a significant tool for analyzing the composition of liquids, gases and solids in 1998 [1]. In this research, we presented the design, fabrication and characterization of an improved gold-based SERS substrate. With fine tuning of the SiO2 thickness we achieved a 3.391 times improvement and achieved an enhancement factor of 1.55 * 10(7) which is 15 times better than the current gold-standard Klarite substrate. Such improvement is ascribed to the localized surface plasmon resonance (SPR) and propagating SPR, which is proved by full-wave finite-difference time-domain simulations.

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“…The sequence numbers (serial number), data status (valid/invalid), channel numbers, the first address of this extension memory, total data capacity and the corresponding measurement information are stored in the record index area. The measurement results are stored in the corresponding format of the data set in the data area [ 29 ]. Generally, the block 0 area is used to store the parameters and record indexes, while the other remaining spaces in the extension memory are allocated to store measurement results.…”

Section: Considerations On Data Acquisitionmentioning

confidence: 99%

Considerations on Circuit Design and Data Acquisition of a Portable Surface Plasmon Resonance Biosensing System

Chang

Chen

Wang

et al. 2015

Sensors

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The aim of this study was to develop a circuit for an inexpensive portable biosensing system based on surface plasmon resonance spectroscopy. This portable biosensing system designed for field use is characterized by a special structure which consists of a microfluidic cell incorporating a right angle prism functionalized with a biomolecular identification membrane, a laser line generator and a data acquisition circuit board. The data structure, data memory capacity and a line charge-coupled device (CCD) array with a driving circuit for collecting the photoelectric signals are intensively focused on and the high performance analog-to-digital (A/D) converter is comprehensively evaluated. The interface circuit and the photoelectric signal amplifier circuit are first studied to obtain the weak signals from the line CCD array in this experiment. Quantitative measurements for validating the sensitivity of the biosensing system were implemented using ethanol solutions of various concentrations indicated by volume fractions of 5%, 8%, 15%, 20%, 25%, and 30%, respectively, without a biomembrane immobilized on the surface of the SPR sensor. The experiments demonstrated that it is possible to detect a change in the refractive index of an ethanol solution with a sensitivity of 4.99838 × 105 ΔRU/RI in terms of the changes in delta response unit with refractive index using this SPR biosensing system, whereby the theoretical limit of detection of 3.3537 × 10−5 refractive index unit (RIU) and a high linearity at the correlation coefficient of 0.98065. The results obtained from a series of tests confirmed the practicality of this cost-effective portable SPR biosensing system.

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Improved polarization contrast method for surface plasmon resonance imaging sensors by inert background gold film extinction

Cited by 11 publications

References 18 publications

High-performance polarization control modulated surface plasmon resonance sensor based on monolayer graphene/Au-NPs architecture for detection of DNA hybridization

High-performance polarization control modulated surface plasmon resonance sensor based on monolayer graphene/Au-NPs architecture for detection of DNA hybridization

Large-area, lithography-free, low-cost SERS sensor with good flexibility and high performance

Considerations on Circuit Design and Data Acquisition of a Portable Surface Plasmon Resonance Biosensing System

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