Improved patient quality of life following intradural extramedullary spinal tumor resection

Abstract

<jats:sec> <jats:title>OBJECTIVE</jats:title> <jats:p>Resection significantly improves the clinical symptoms and functional outcomes of patients with intradural extramedullary tumors. However, patient quality of life following resection has not been adequately investigated. The aim in this retrospective analysis of prospectively collected quality of life outcomes is to analyze the efficacy of resection of intradural extramedullary spinal tumors in terms of quality of life markers.</jats:p></jats:sec> <jats:sec> <jats:title>METHODS</jats:title> <jats:p>A retrospective review of a single institutional neurosurgical administrative database was conducted to analyze clinical data. The Oswestry Disability Index (ODI), visual analog scale (VAS) for pain, and the EQ-5D-3 L descriptive system were used to analyze quality of life preoperatively, less than 1 month postoperatively, 1–3 months postoperatively, 3–12 months postoperatively, and more than 12 months postoperatively.</jats:p></jats:sec> <jats:sec> <jats:title>RESULTS</jats:title> <jats:p>The ODI scores increased perioperatively at the &lt; 1-month follow-up from 36 preoperatively to 47. Relative to preoperative values, the ODI score decreased significantly at 1–3, 3–12, and &gt; 12 months to 23, 17, and 20, respectively. VAS scores significantly decreased from 6.1 to 3.5, 2.4, 2.0, and 2.9 at the &lt; 1-month, 1- to 3-, 3- to 12-, and &gt; 12-month follow-ups, respectively. EQ-5D mobility significantly worsened at the &lt; 1-month follow-up but improved at the 3- to 12-and &gt; 12-month follow-ups. EQ-5D self-care significantly worsened at the &lt; 1-month follow-up but significantly improved by the 3- to 12-month follow-up. EQ-5D usual activities improved at the 1- to 3-, 3- to 12-, and &gt; 12-month follow-ups. EQ-5D pain and discomfort significantly improved at all follow-up points. EQ-5D anxiety and depression significantly improved at 1- to 3-month and 3- to 12-month follow-ups.</jats:p></jats:sec> <jats:sec> <jats:title>CONCLUSIONS</jats:title> <jats:p>Resection of intradural extramedullary spine tumors appears to significantly improve patient quality of life by decreasing patient disability and pain and by improving each of the EQ-5D domains.</jats:p></jats:sec>

Surgical outcome of intradural extramedullary spinal cord tumors - Our experience at a tertiary health care center

“…Like previous studies, in our series there was improvement in neurology in 91.67% of patients with complete recovery in 75% of the cases and not a single case deteriorated neurologically post-surgery. This is consistent with results from other studies that showed good outcomes in 87% of patients 7,24 .…”

Differentiating between spinal schwannomas and meningiomas using MRI: A focus on cystic change

“…Intradural extramedullary spinal tumors are the most common type of spinal tumors that may result in serious morbidity related to progressive neurologic deficits. [1][2][3] Among them, meningiomas and schwannomas are the two most common histologic subtypes, which comprise 55-90% of all intradural extramedullary spinal tumors. [4,5] Although both tumors are mostly benign, there is a substantial difference between the surgical techniques for removing each.…”

Intradural Extramedullary Metastasis of the Upper Thoracic Spine &ndash; Case Report and Literature Review

“…4,9,12,14 Postoperative outcome in our patient confirm literature statement that surgical resection of IEM improves patient's quality of life by reducing the pain intensity and improving the neurological status. 12,17…”