Improved One-Year Survival afterAcute Myocardial Infarction in Iceland between 1986 and 1996

Abstract

During the last decade the treatment of patients with acute myocardial infarction (AMI) has changed dramatically. In order to evaluate the overall impact of these changes on mortality and morbidity, we collected data on all patients hospitalized for AMI in Reykjavik, Iceland, during the calendar years of 1986 and 1996. Demographical characteristics of AMI patients did not change significantly between study periods. One-year mortality decreased from 26.3 to 19.7% (p < 0.05). Patients discharged with aspirin or β-antagonists as well as those who received thrombolytic therapy had decreased 1-year mortality both years. Patients discharged with diuretics, digoxin or antiarrhythmics had increased 1-year mortality. We conclude that the 25% reduction in 1-year mortality is partially due to changes in therapy.

Postmyocardial Infarction Mortality in Relation to Depression: A Systematic Critical Review

“…In 4 of the 7 studies accepted to be of good quality, non-significant results regarding depression and post-MI mortality were reported [13, 17, 23, 31; ]Appendix 1], whereas in the three other studies a positive relation was reported [[5, 21, 26]; Appendix1]. In 10 of the 20 studies of medium quality, a positive relation was reported [1, 2, 8,14,15,16, 19, 20, 24, 25; ]Appendix 1], whereas in the remaining ten studies a non-significant relation was reported [3, 6, 10, 12, 18, 22,27,28,29,30]; Appendix 1].…”

“…In 4 of the 8 studies, where depression was assessed based on interviews, a positive relation between depression and post-MI mortality was found [5, 16, 21, 26; ]Appendix 1], whereas a non-significant relation was reported in the other four studies [[13, 22, 23, 31; ]Appendix 1]. In 5 of the 9 studies, where the BDI was applied, a positive relation was reported [1, 8, 14, 15, 26; ]Appendix 1], whereas a non-significant relation was reported in three studies [18, 27, 30; ]Appendix 1], and the sixth and last study [7]; Appendix 1] failed to report on this.…”

“…12 of 18 studies, in which the data collection started before 1994, reported a positive relation between depression and post-MI mortality [[1, 2, 5, 8, 9, 11, 14, 15,19,20,21, 25; ]Appendix 1], in four studies a non-significant relation was reported [3, 6, 10, 28; ]Appendix 1], and the last two studies [4, 7]; Appendix 1] failed to report on this. For the twelve studies with data collection starting after 1994, a positive relation was reported in three studies [[16, 24, 26]; Appendix 1], and a non-significant relation was reported in the remaining nine studies [12, 13, 17, 18, 22, 23, 27, 29, 30; ]Appendix 1].…”

“…For the twelve studies with data collection starting after 1994, a positive relation was reported in three studies [[16, 24, 26]; Appendix 1], and a non-significant relation was reported in the remaining nine studies [12, 13, 17, 18, 22, 23, 27, 29, 30; ]Appendix 1]. The studies with data collection starting after 1994 were generally of a better methodological quality, with four studies being of good quality [13, 17, 23, 26; ]Appendix 1], of which three reported a non-significant relation between depression and post-MI mortality, and the remaining eight studies were of medium quality [12, 16, 18, 22, 24, 27, 29, 30; ]Appendix 1[,] than those with data collection starting before 1994, with two studies being of good quality [5, 21; ]Appendix 1], eleven being of medium quality [1,2,3, 6, 8, 10, 14, 15, 19, 20, 25; ]Appendix 1], and four studies being of low quality [4, 7, 9, 11; ]Appendix 1].…”

“…Articles that fitted these criteria were given an identification number [1,2,3,4,5,6,7,8,9,10,11,12,13,14,15,16,17,18,19,20,21,22,23,24,25,26,27,28,29,30,31] Appendix 1]. They were then systematically reviewed for descriptive information for quality issues.…”