The article presents the results of the diagnostic effectiveness of non-invasive methods for assessing the state of the liver parenchyma, such as liver elastography (transient, strain and 2D shear waves) and the current trend in medical imaging contrast-enhanced ultrasound (CEUS). 25 people aged 31 to 72 years with chronic viral hepatitis B and C were examined. All patients underwent multiparametric ultrasound examination of the liver: ultrasound in B-mode, color Doppler’s mapping of liver vessels, elastography (transient, strain and 2D shear waves), CEUS with 1,0 ml of the contrast agent and subsequent analysis of contrast parameters in the arterial, portal and late venous phases. The liver biopsy was used as a reference method, which was performed after receiving voluntary informed consent in 100 % of cases.