Abstract:Although ceramic prostheses have been successfully used in conventional total hip arthroplasty (THA) for many decades, ceramic materials have not yet been applied for hip resurfacing (HR) surgeries. The objective of this study is to investigate the mechanical reliability of silicon nitride as a new ceramic material in HR prostheses. A finite element analysis (FEA) was performed to study the effects of two different designs of prostheses on the stress distribution in the femur-neck area. A metallic (cobalt-chro… Show more
“…But, are things actually so simple? The need for high toughness and structural reliability would suggest driving our attention on Si 3 N 4 ceramics as a primary covalent-bonded candidate for arthroplastic joint applications [132,133,134,135]. Toughness of a commercially available Si 3 N 4 biomaterial (manufactured by Amedica Corporation, Salt Lake City, UT, USA) has been reported as two to three times higher than that of monolithic Al 2 O 3 and was also appreciably higher than that of the leading Al 2 O 3 -ZrO 2 composites (Composite A in the previous section), toughened by polymorphic transformation [136].…”
Section: Experimental Evidence and Future Strategiesmentioning
Which intrinsic biomaterial parameter governs and, if quantitatively monitored, could reveal to us the actual lifetime potential of advanced hip joint bearing materials? An answer to this crucial question is searched for in this paper, which identifies ceramic bearings as the most innovative biomaterials in hip arthroplasty. It is shown that, if in vivo exposures comparable to human lifetimes are actually searched for, then fundamental issues should lie in the physical chemistry aspects of biomaterial surfaces. Besides searching for improvements in the phenomenological response of biomaterials to engineering protocols, hip joint components should also be designed to satisfy precise stability requirements in the stoichiometric behavior of their surfaces when exposed to extreme chemical and micromechanical conditions. New spectroscopic protocols have enabled us to visualize surface stoichiometry at the molecular scale, which is shown to be the key for assessing bioceramics with elongated lifetimes with respect to the primitive alumina biomaterials used in the past.
“…But, are things actually so simple? The need for high toughness and structural reliability would suggest driving our attention on Si 3 N 4 ceramics as a primary covalent-bonded candidate for arthroplastic joint applications [132,133,134,135]. Toughness of a commercially available Si 3 N 4 biomaterial (manufactured by Amedica Corporation, Salt Lake City, UT, USA) has been reported as two to three times higher than that of monolithic Al 2 O 3 and was also appreciably higher than that of the leading Al 2 O 3 -ZrO 2 composites (Composite A in the previous section), toughened by polymorphic transformation [136].…”
Section: Experimental Evidence and Future Strategiesmentioning
Which intrinsic biomaterial parameter governs and, if quantitatively monitored, could reveal to us the actual lifetime potential of advanced hip joint bearing materials? An answer to this crucial question is searched for in this paper, which identifies ceramic bearings as the most innovative biomaterials in hip arthroplasty. It is shown that, if in vivo exposures comparable to human lifetimes are actually searched for, then fundamental issues should lie in the physical chemistry aspects of biomaterial surfaces. Besides searching for improvements in the phenomenological response of biomaterials to engineering protocols, hip joint components should also be designed to satisfy precise stability requirements in the stoichiometric behavior of their surfaces when exposed to extreme chemical and micromechanical conditions. New spectroscopic protocols have enabled us to visualize surface stoichiometry at the molecular scale, which is shown to be the key for assessing bioceramics with elongated lifetimes with respect to the primitive alumina biomaterials used in the past.
“…The less detrimental biological response may give a reduced number of revisions as an end result. However, whereas the wear and tribofilm formation of Si 3 N 4 sliding against itself in water have been investigated, 10 , 11 , 14 , 15 , 21 there is a lack of knowledge on the wear and tribofilm formation in PBS and bovine serum and also regarding the solubility of the wear particles.…”
Many of the failures of total joint replacements are related to tribology, i.e., wear of the cup, head and liner. Accumulation of wear particles at the implants can be linked to osteolysis which leads to bone loss and in the end aseptic implant loosening. Therefore it is highly desirable to reduce the generation of wear particles from the implant surfaces.
Silicon nitride (Si3N4) has shown to be biocompatible and have a low wear rate when sliding against itself and is therefore a good candidate as a hip joint material. Furthermore, wear particles of Si3N4 are predicted to slowly dissolve in polar liquids and they therefore have the potential to be resorbed in vivo, potentially reducing the risk for aseptic loosening.
In this study, it was shown that α-Si3N4-powder dissolves in PBS. Adsorption of blood plasma indicated a good acceptance of Si3N4 in the body with relatively low immune response. Si3N4 sliding against Si3N4 showed low wear rates both in bovine serum and PBS compared with the other tested wear couples. Tribofilms were built up on the Si3N4 surfaces both in PBS and in bovine serum, controlling the friction and wear characteristics.
“…Laboratory investigations using finite element analyses support the use of silicon nitride in load-bearing hip resurfacing components; these differ from hip replacement in that the diseased femoral head is resurfaced with a prosthetic cap, rather than being cut out and replaced entirely. 32 Stress distributions in the proximal femur bone with implanted silicon nitride hip prostheses are similar to those of intact, healthy bone. Mazzocchi et al investigated silicon nitride ceramics for their potential use in orthopaedic implants, and validated several properties that are critical to biomedical applications, such as wetting behavior and wear performance that simulates conditions typical of a hip joint prosthesis.…”
Section: Tribological Properties Of Silicon Nitridementioning
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