“…Two studies reported the influence of carotid disease but these were not included in this group as carotid disease is not primarily associated with all strokes and carotid disease was poorly defined. 16,37 Nine studies 17,19,24,27,28,31,38,44,59 reported the influence of cerebrovascular disease on late survival resulting in a pooled HR 1.57 (95% CI 1.40e1.77) I 2 ¼ 0%. The presence of carotid disease had a HR 1.27 (95% CI 0.93e1.73) I 2 ¼ 0%.…”