Improved left ventricular mass index in children after renal transplantation

Becker-Cohen, Rachel; Nir, Amiram; Ben-Shalom, Efrat; Rinat, Choni; Feinstein, Sofia; Farber, Benjamin; Frishberg, Yaacov

doi:10.1007/s00467-008-0855-5

Cited by 40 publications

(37 citation statements)

References 20 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Moreover, it was determined that both types of dialysis did not alter LASFI and similar results were obtained in both patient groups in terms of volume load control. Impairment in the LA systolic functions in line with increase in renal insufficiency stage (29) was demonstrated also in the present study and our results were consistent with the literature. Decrease in LA volume, SA/Ao ratio, and LASFI may be suggested as the predictors of LA remodeling (30).…”

Section: Discussionsupporting

confidence: 82%

Evaluation of left atrial functions in children with chronic renal failure

Demirpençe¹,

Güven²,

Meşe³

et al. 2014

Anadolu Kardiyol Derg

View full text Add to dashboard Cite

Objective: One-quarter of deaths in children with chronic renal failure is due to cardiovascular complications. Conventional echocardiographic methods are insufficient for evaluating systolic functions in children with chronic renal failure. The aim of the present study was to investigate cardiac functions in children with chronic renal failure by evaluating left atrial volume and functions. Methods: The present cross-sectional observational study included 44 children undergoing dialysis, 16 children with chronic renal failure but not yet on dialysis, and 20 healthy control subjects. Transthoracic echocardiography was performed for all children. Variables regarding to left ventricle and atrium (left atrial systolic force, left atrial systolic force index, left atrial volume, left ventricular mass index, and relative wall thickness) were measured using two-dimensional and M-mode echocardiography. Results: Left atrial systolic force index was negatively correlated with systolic blood pressure and left ventricular mass (p=0.01, r=0.266 and p=0.02, r=0.347, respectively). However, it was positively correlated with both early and late diastolic mitral inflow velocity (r=0.518, p=0.001 and r=0.828, p=0.001, respectively). There were no significant difference among the groups in terms of left atrial systolic force index and left atrial volume. However, left atrial systolic force index was higher in children with chronic renal failure but not yet on dialysis. Conclusion: Left atrial systolic force was negatively correlated with systolic blood pressure and left ventricular mass. These findings suggested that evaluating left atrial systolic force and left atrial volume were useful to determine diastolic dysfunction and the necessity of dialysis in patient with chronic renal failure. (Anadolu Kardiyol Derg 2014; 14: 280-5)

show abstract

Section: Discussionsupporting

confidence: 82%

Evaluation of left atrial functions in children with chronic renal failure

Demirpençe¹,

Güven²,

Meşe³

et al. 2014

Anadolu Kardiyol Derg

View full text Add to dashboard Cite

show abstract

“…Most of these studies show the persistence of cardiac hypertrophy, [32][33][34] but some report improvement post-transplant. 35 As in adults, hypertension is the main cause of cardiac hypertrophy in children before ESRD or post-transplant. Elevated parathyroid hormone (PTH) might contribute to progression of LVH in children with stage 2-4 CKD 36 and hypertension associated with volume overload has been linked to the development of LVH in the dialysis population.…”

Section: Lvh Is the Most Common Cardiac Abnormality In Children With Ckdmentioning

confidence: 99%

“…1 In contrast, these rates were 35.6 (dialysis) and 3.5 (transplant) per 1000 patient-years at risk for children aged 0-19 years with ESRD according to [2006][2007][2008] data from the US Renal Data System (USRDS). 2 These large discrepancies in mortality rates exist despite the widespread availability of state-of-the-art renal replacement therapy and substantial advances in the care of children with CKD over the last 3 decades.…”

mentioning

confidence: 99%

Cardiovascular Disease in Children with Chronic Kidney Disease

Mitsnefes

2012

Journal of the American Society of Nephrology

317

149

View full text Add to dashboard Cite

More than a decade ago, cardiovascular disease (CVD) was recognized as a major cause of death in children with advanced CKD. This observation has sparked the publication of multiple studies assessing cardiovascular risk, mechanisms of disease, and early markers of CVD in this population. Similar to adults, children with CKD have an extremely high prevalence of traditional and uremia-related CVD risk factors. Early markers of cardiomyopathy, such as left ventricular hypertrophy and dysfunction, and early markers of atherosclerosis, such as increased carotid artery intima-media thickness, carotid arterial wall stiffness, and coronary artery calcification, are frequently present in these children, especially those on maintenance dialysis. As a population without preexisting symptomatic cardiac disease, children with CKD potentially receive significant benefit from aggressive attempts to prevent and treat CVD. Early CKD, before needing dialysis, is the optimal time to both identify modifiable risk factors and intervene in an effort to avert future CVD. Slowing the progression of CKD, avoiding long-term dialysis and, if possible, conducting preemptive transplantation may represent the best strategies to decrease the risk of premature cardiac disease and death in children with CKD.

show abstract

“…Other factors include CIMT, regression of left ventricular hypertrophy after transplant, and high blood pressure [40].…”

Section: Discussionmentioning

confidence: 99%

Evaluation of Ultrasensitive C-Reactive Protein as a Cardiovascular Risk Marker in Pediatric Patients with End-Stage Renal Disease on Peritoneal Dialysis

Orellana¹

2017

J Clin Nephrol Ren Care

View full text Add to dashboard Cite

Background: Patients with End-Stage Renal Disease (ESRD) on Peritoneal Dialysis (PD) experience high morbidity and mortality due to Cardiovascular (CV) disease. In pediatric patients, CV problems include Left Ventricular (LV) abnormalities, hypertension, and arrhythmias. The classic CV Risk Factors (RF) are not adequate to identify CV risk in these patients, but inflammation markers such as Ultrasensitive C-Reactive Protein (USCRP) may be useful in detecting early CV disease. The objective was to assess CV risk in pediatric patients with ESRD on PD and evaluate the utility of USCRP as a CV risk marker.

show abstract

Improved left ventricular mass index in children after renal transplantation

Cited by 40 publications

References 20 publications

Evaluation of left atrial functions in children with chronic renal failure

Evaluation of left atrial functions in children with chronic renal failure

Cardiovascular Disease in Children with Chronic Kidney Disease

Evaluation of Ultrasensitive C-Reactive Protein as a Cardiovascular Risk Marker in Pediatric Patients with End-Stage Renal Disease on Peritoneal Dialysis

Contact Info

Product

Resources

About