Improved Inter-Subject Alignment of the Lumbosacral Cord for Group-Level In Vivo Gray and White Matter Assessments: A Scan-Rescan MRI Study at 3T
Silvan Büeler,
Patrick Freund,
Thomas M. Kessler
et al.
Abstract:INTRODUCTION: Magnetic resonance imaging (MRI) enables the investigation of pathological changes in gray and white matter at the lumbosacral enlargement (LSE) and conus medullaris (CM). However, conducting group-level analyses of MRI metrics in the lumbosacral spinal cord is challenging due to variability in CM size, lack of established image-based landmarks, and unknown scan-rescan reliability. This study aimed to improve inter-subject alignment of the lumbosacral cord to facilitate group-level analyses of MR… Show more
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