Improved hypoglycemic effect of anthocyanin extract combination from red rice and black soybean

Rahayu, Wahidah Mahanani; Astuti, Mary; Marsono, Yustinus

doi:10.1088/1742-6596/1146/1/012015

Cited by 2 publications

(1 citation statement)

References 19 publications

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“…Peonidin-3-O-glucoside can inhibit the tumor necrosis factor alpha (TNF-α) signaling pathway so that it has the potential to be antiinflammatory [16]. A previous study reported that brown rice extract consumed by hyperglycemic rats induced using streptozotocin (STZ) and nicotinamide (NA) could reduce blood glucose up to 50.9% [17]. In vivo study on dyslipidemia mice treated with anthocyanin from pigmented rice showed decreased cholesterol levels, malondialdehyde (MDA), and the expression of genes involved in obesity [18].…”

Section: ■ Introductionmentioning

confidence: 99%

Java Red Rice (<i>Oryza sativa</i> L.) Nutritional Value and Anthocyanin Profiles and Its Potential Role as Antioxidant and Anti-Diabetic

2021

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This study investigates nutritional value, amino acid profile, and total anthocyanin in pigmented rice as an antioxidant and anti-diabetic agent. Six rice varieties were extracted using 0.1% HCl in methanol, namely four red rice, one black rice, and one white rice. Rice extract was used for proximate analysis and amino acid profiling. Total anthocyanin was measured and identified by ultraviolet-visible (UV-Vis) spectrophotometer and thin-layer chromatography (TLC). The antioxidant activity was determined using Ferric-reducing antioxidant power (FRAP) assay, and the α-amylase enzyme-inhibited by anthocyanin extract of red rice as anti-diabetic was measured. The study result showed that the proximate level (carbohydrate, protein, lipid, water, and ash) in pigmented rice was different. Cempo merah red rice is a source of amino acids, both essential and non-essential amino acids that act as good nutrition. The highest total anthocyanin level between red rice varieties of 10.87 mg/g was found in Aek sibundong red rice. High biological function activities as an antioxidant were indicated by Aek sibundong red rice with an IC50 value of 6.65 µg/mL. Aek sibundong red rice shows the lowest IC50 value of 144.46 µg/mL in anti-diabetic activity. Thus, Aek sibundong red rice may have the potential as α-amylase inhibitor for diabetes prevention.

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Section: ■ Introductionmentioning

confidence: 99%

Java Red Rice (<i>Oryza sativa</i> L.) Nutritional Value and Anthocyanin Profiles and Its Potential Role as Antioxidant and Anti-Diabetic

2021

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Nutritional and Medicinal Value of Red Rice

Kothapalli

Kale

Dharade

et al. 2023

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Background: Various varieties of rice (Oryza sativa) have been exploited for a variety of purposes since ancient times, with the integration into foods, cosmetics, and pharmaceutical products. A huge diversity is seen in the cultivated rice variety based on regions, area, and climatic conditions responsible for variation in chemical composition leading to enriched supplements beneficial for health conditions. Among the varieties available, red rice extract is now increasingly recognized for its antioxidant, anti-inflammatory activity, anti-diabetic, anti-hyperlipidemic activity, and bone formation. Objective: There is a need to validate the nutritional and supplement values through appropriate analytical and pharmacological studies and create awareness for the end users regarding the value of red rice. Results: In the present article attempt is done to reviewthe variety of red rice based on geographical origin, and the impact on nutritional and medicinal value. Further elaborating the extraction techniques which can help optimize the extraction efficiency of polyphenols known for their antioxidant properties. Polyphenolic phytoconstituents belonging to phenolic acids, and flavonoids include, flavonols, flavones, flavanols, flavanones, and isoflavones, to name a few. Anthocyanins, and proanthocyanidins make the pigment part of the outer layer and bran of the rice and contain the monomers of catechin, epicatechin, gallocatechin, and epigallocatechin units. The quantification of the phytoconstituents using chromatographical methods can help in evaluation of the red rice for its quality and design formulation with desired efficacy. Conclusion: With the vast varieties of red rice available, quantification of important bio-actives can help in maintaining quality of final product. Various targeted pharmacological actions reported include anti-inflammatory, antihyperlipidemic, antidiabetic, anticancer and antioxidant produced by the rice, mainly by virtue of the polyphenolic content, contribute in achieving a value to rice as nourishment and a safe therapeutic product which can be consumed as a nutraceutical or pharmaceutical ingredient.

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Improved hypoglycemic effect of anthocyanin extract combination from red rice and black soybean

Cited by 2 publications

References 19 publications

Java Red Rice (<i>Oryza sativa</i> L.) Nutritional Value and Anthocyanin Profiles and Its Potential Role as Antioxidant and Anti-Diabetic

Java Red Rice (<i>Oryza sativa</i> L.) Nutritional Value and Anthocyanin Profiles and Its Potential Role as Antioxidant and Anti-Diabetic

Nutritional and Medicinal Value of Red Rice

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