Improved genistein loading and release on electrospun chitosan nanofiber blends

Novel mineralized electrospun chitosan/PVA/TiO2 nanofibrous composites for potential biomedical applications: computational and experimental insights

“…[4][5][6] Electrospun nanobrous materials can be fabricated to yield high porosity and a high surface area-to-volume ratio, which makes them qualify for several applications such as drug delivery, tissue engineering, wound healing, antibacterial agents, sensing, and food packaging. [7][8][9][10][11][12][13][14] Nanobrous composite materials are composed of either natural or synthetic polymers and play a crucial role especially in tissue attachment and regeneration in the biomedical eld owing to a high surface area in addition to their ability to provide high capacity of stabilized seeded cells entrapped on their mesh surfaces. [15][16][17][18] Chitosan (Cs), an amino sugar, is a natural polysaccharide polymer, which exists in nature in the cell walls of Zygomycetes or chitin.…”

Genistein Loaded Nanofibers Protect Spinal Cord Tissue Following Experimental Injury in Rats

“…Electrospinning was used to fabricate CS/PVA nanofibers using acetic acid/distilled water solution mixture as a solvent (Jiang, Zhao et al 2007). We have previously described the fabrication and characterization of nanofibers loaded with genistein (Ibrahim S 2016). Briefly; Optimum preparation conditions for CS/PVA nanofibers (Figure 1), were established as follows; polymers volume ratio 30/70 CS/PVA, concentration of mixture 50%, applied voltage 25 KV, flow rate 0.7 ml/hour, and tip to collector distance (TCD) 10 cm, followed by physical crosslinking (Ibrahim S 2016).…”

“…Cytotoxicity of crosslinked CS/PVA nanofibers was previously described (Ibrahim S 2016) using MTT assay (ATCC® 30-1010K) on human fibroblast cells (ATCC CCL-75 W1 38).…”

“…Scanning electron micrograph of nanofibers, showing uniform structure and diameter of nanofibers. We previously(Ibrahim S., et al 2016) reported the optimum conditions for preparation of CS/PVA nanofibers (volume ratio 30/70 CS/PVA, concentration of mixture 50%, voltage 25 KV, flow rate 0.7 ml/hr., and tip-to-collector distance (TCD) 10 cm.…”

Electrospun functionalized magnetic polyamide 6 composite nanofiber: Fabrication and stabilization

“…This method uses electrostatic potential between two electrodes. The first electrode is a spinning electrode which performs a drawing of a certain liquid (polymer solution, sol, and melt) toward the second electrode . Properties of spun materials are affected by chemical compositions of the polymers and spinning parameters such as the electric field intensity and conductivity.…”