Improved Gas Exchange Performance of the Intravascular Oxygenator by Active Blood Mixing

Tao, Weike; Schroeder, Tyrus; Bidani, A.; Cardenas, Victor J.; Nguyen, Phoung-dung J.; Bradford, Darien W.; Traber, Daniel L.; Zwischenberger, Joseph B.

doi:10.1097/00002480-199407000-00056

Cited by 6 publications

(1 citation statement)

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“…The first approach is generation of active mixing within the catheter. This was initially attempted using an intraaortic balloon pump close to the shaft of the IVOX catheter [56]. However, the membrane fibers were not fixed and fiber movement opposed active mixing.…”

Section: Future Directions and Devices In Developmentmentioning

confidence: 99%

Bench to bedside review: Extracorporeal carbon dioxide removal, past present and future

et al. 2012

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Acute respiratory distress syndrome (ARDS) has a substantial mortality rate and annually affects more than 140,000 people in the USA alone. Standard management includes lung protective ventilation but this impairs carbon dioxide clearance and may lead to right heart dysfunction or increased intracranial pressure. Extracorporeal carbon dioxide removal has the potential to optimize lung protective ventilation by uncoupling oxygenation and carbon dioxide clearance. The aim of this article is to review the carbon dioxide removal strategies that are likely to be widely available in the near future. Relevant published literature was identified using PubMed and Medline searches. Queries were performed by using the search terms ECCOR, AVCO2R, VVCO2R, respiratory dialysis, and by combining carbon dioxide removal and ARDS. The only search limitation imposed was English language. Additional articles were identified from reference lists in the studies that were reviewed. Several novel strategies to achieve carbon dioxide removal were identified, some of which are already commercially available whereas others are in advanced stages of development.

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Section: Future Directions and Devices In Developmentmentioning

confidence: 99%

Bench to bedside review: Extracorporeal carbon dioxide removal, past present and future

et al. 2012

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Intravascular Membrane Oxygenation and Carbon Dioxide Removal with Permissive Hypercapnia — New Concepts in the Management of Respiratory Failure

Zwischenberger¹,

Tao²,

CardenasJr.³

et al. 1995

Assisted Circulation 4

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Extracorporeal carbon dioxide removal (ECCO2R) in respiratory deficiency and current investigations on its improvement: a review

Manap

Wahab

2016

J Artif Organs

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The implementation of extracorporeal carbon dioxide removal (ECCOR) as one of the extracorporeal life support system is getting more attention today. Thus, the objectives of this paper are to study the clinical practice of commercial ECCOR system, current trend of its development and also the perspective on future improvement that can be done to the existing ECCOR system. The strength of this article lies in its review scope, which focuses on the commercial ECCOR therapy in the market based on membrane lung and current investigation to improve the efficiency of the ECCOR system, in terms of surface modification by carbonic anhydrase (CA) immobilization technique and respiratory electrodialysis (R-ED). Our methodology approach involves the identification of relevant published literature from PubMed and Web of Sciences search engine using the terms Extracorporeal Carbon Dioxide Removal (ECCOR), Extracorporeal life support, by combining terms between ECCOR and CA and also ECCOR with R-ED. This identification only limits articles in English language. Overall, several commercial ECCOR systems are known and proven safe to be used in patients in terms of efficiency, safety and risk of complication. In addition, CA-modified hollow fiber for membrane lung and R-ED are proven to have good potential to be applied in conventional ECCOR design. The detailed technique and current progress on CA immobilization and R-ED development were also reviewed in this article.

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Improved Gas Exchange Performance of the Intravascular Oxygenator by Active Blood Mixing

Cited by 6 publications

References 0 publications

Bench to bedside review: Extracorporeal carbon dioxide removal, past present and future

Bench to bedside review: Extracorporeal carbon dioxide removal, past present and future

Intravascular Membrane Oxygenation and Carbon Dioxide Removal with Permissive Hypercapnia — New Concepts in the Management of Respiratory Failure

Extracorporeal carbon dioxide removal (ECCO2R) in respiratory deficiency and current investigations on its improvement: a review

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