Improved estimation of contact compliance via atomic force microscopy using a calibrated cantilever as a reference sample

Salerno, Marco

doi:10.1016/j.measurement.2012.05.011

Cited by 7 publications

(8 citation statements)

References 34 publications

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“…Additionally, uncertainties are inevitably caused by the probe, such as tip shape, tip size, contact point and Poisson ratio. 15 Therefore, the relative difference between samples is more meaningful for studying the mechanical properties of cells before and aer drug treatment. Actually, cell physical changes signicantly contribute to cellular growth.…”

Section: Resultsmentioning

confidence: 99%

“…The Young's modulus is actually the result of complex tting and several hypotheses of contact regime and tip properties, which lead to signicant experimental uncertainty. 15 However, the relative modulus values show a close correlation with the true sample properties. Thus, comprehensive and detailed data can be obtained for single cell analysis.…”

Section: Introductionmentioning

confidence: 92%

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Evaluation of 5-fluorouracil-treated lung cancer cells by atomic force microscopy

Jiang

et al. 2019

Anal. Methods

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Section: Resultsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 92%

Evaluation of 5-fluorouracil-treated lung cancer cells by atomic force microscopy

Jiang

et al. 2019

Anal. Methods

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“…The importance of SEM, in combination with AFM or as a faster alternative when no 3D surface topography is required, was confirmed in Salerno (2012b). This work focused on the standard restorative composite VD.…”

Section: Surface Characterization Of Restorative Compositesmentioning

confidence: 89%

“…These composites were studied in a simplified model version, without the use of a coupling agent bonding the fillers and the matrix. AFM had already been used in Salerno (2012b) to measure the contact stiffness (see Figure 5), but in this work (Salerno, 2012a) the authors moved on to quantitative evaluation of the elastic modulus, which is known to be a critical step (Salerno, 2012b). Concurrently, DMA was used for cross-checking the AFM values of modulus, and a good agreement was observed between the two techniques ( Figure 4C).…”

Section: Elastic Properties Of Restorative Compositesmentioning

confidence: 92%

“…These porous titania nanotubes have been investigated so far mainly for applications in optics and photonics, thanks to the photocatalytic activity of titania (Mor et al, 2006). However, they could also be used as the surface modification of Ti implants in dentistry and orthopedics, similar to APA (Salerno, 2012b) and without the need for preliminary Al coating.…”

Section: Figure 5 | (A) Afm Height Image and (B)mentioning

confidence: 99%

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Dentistry on the Bridge to Nanoscience and Nanotechnology

Salerno

Diaspro

2015

Front. Mater.

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Dentistry is the area of medical sciences that is most resistant to the introduction of the novel methods arisen from the development of nanoscience and nanotechnology in the last 20 years. Without moving on to science-fiction-like views pointing to times far ahead in the future, we show that the available nanoscale devices and processes of current science and technology, partly inherited from the areas of microscopy and microelectronics, have already proven to be useful for research and development in different fields of dental research. To this goal, we review some results obtained in the last few years at our Institute in the area of dental materials and their characterization, which showed successful application of our background in microscopy and nanoengineering.Keywords: dental materials, microscopy, surface roughness, nanofabrication, resin composites, implants THE BROAD SCOPE OF DENTISTRYDentistry is considered to be a branch of medicine, such as orthopedics or physiology or neurology. In fact, while based on common foundations of medicine, dentistry is a large stand-alone area, which has its own grasps to the different fields mentioned above (American Dental Association, 2014). For example, topics of periodontal ligament health and dental implant osteointegration clearly relate to a peculiar "dental orthopedics"; the fact that teeth are not a mineralized appendix but rather a living organ in a living environment (gingiva, oral liquids) involves a specific "dental physiology"; the sensitivity of the living tooth, in connection with the pulp and related nerves, can be associated to a possible "dental neurology." Indeed, the oral environment, which is the place where dental functions are operated, is one of the most complex ones in the human body.As a result, within the dental area several specialized disciplines exist (see Figure 1). Conservative dentistry aims to maintain the original denture and largely overlaps with restorative dentistry, the latter encompassing prosthodontics, periodontics, and endodontics. Prosthodontics (or prosthetic dentistry) is required in case of massive irreversible tooth damage that cannot be fixed with simple resin composite filling, and requires the use of prosthesis for teeth, namely crowns, bridges, and even whole dentures. Periodontics (or periodontology) addresses the diseases of the periodontum, i.e., the teeth ligaments. Endodontics focuses on therapy of the root canals and connected pulp diseases. Oral surgery relates to the extraction of teeth that cannot be saved anymore and should be replaced by implants, and is usually combined with maxillo-facial surgery, extending the treated area around the denture. Prosthodontics, periodontics, and surgery correlate to implantology, which deals with the installation of dental implants. Orthodontics concerns the alignment and straightening of teeth, as well as fixing midface and mandibular growth issues. Pedodontics (or pediatric dentistry) relates to the specific dental issues of children's temporary dentures. Of course, oral...

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A new quantitative experimental approach to investigate single cell adhesion on multifunctional substrates

Canale

Petrelli

Salerno

et al. 2013

Biosensors and Bioelectronics

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Improved estimation of contact compliance via atomic force microscopy using a calibrated cantilever as a reference sample

Cited by 7 publications

References 34 publications

Evaluation of 5-fluorouracil-treated lung cancer cells by atomic force microscopy

Evaluation of 5-fluorouracil-treated lung cancer cells by atomic force microscopy

Dentistry on the Bridge to Nanoscience and Nanotechnology

A new quantitative experimental approach to investigate single cell adhesion on multifunctional substrates

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