Improved cell adhesion to flat and porous plasma-treated poly-ε-caprolactone samples

Jacobs, Tinneke; Declercq, Heidi; Cornelissen, Ria; Dubruel, Peter; Leys, Christophe; Morent, Rino

doi:10.1016/j.surfcoat.2013.06.001

Cited by 33 publications

(30 citation statements)

References 22 publications

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“…This suggests that either: (1) it is not a problem thanks to the better pore interconnectivity or (2) no attention was paid to it. The latter seems more likely, based on the results found by Jacobs et al [71] for a plasma-activated rapid-prototyped scaffolds. In either case, more structural studies are required to analyze this, as well as a transfer of some of the results found for traditional scaffolds to the rapid prototyped ones.…”

Section: Rapid Prototypingmentioning

confidence: 94%

“…7F2 mouse osteoblasts were seeded in both cases, giving similar results: enhanced adhesion and differentiation (higher levels of ALP and osteocalcin), and accelerated formation of mixed mineralization, all indications of increased osseointegrating properties. In 2012, Jacobs et al [71] performed a more systematic study of different plasma discharge gasses (Ar, He and air) on PCL printed scaffolds, using a medium pressure parallel-plate system (5 kPa, 1-2 W, 30-300 s). Short treatment times resulted in the formation of a wettability gradient toward the center of the scaffold, as visualized by a standardized ink-staining method [72].…”

Section: Rapid Prototypingmentioning

confidence: 99%

See 1 more Smart Citation

Plasma Science and Technology - Progress in Physical States and Chemical Reactions

Mieno¹

2016

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Non-thermal plasma technology is one of those techniques that suffer relatively little from diffusion limits, slow kinetics, and complex geometries compared to more traditional liquid-based chemical surface modification techniques. Combined with a lack of solvents, preservation of the bulk properties, and fast treatment times; it is a well-liked technique for the treatment of materials for biomedical applications. In this book chapter, a review will be given on what the scientific community determined to be essential to obtain appropriate scaffolds for tissue engineering and how plasma scientists have used non-thermal plasma technology to accomplish this. A distinction will be made depending on the scaffold fabrication technique, as each technique has its own set of specific problems that need to be tackled. Fabrication techniques will include traditional fabrication methods, rapid prototyping, and electrospinning. As for the different plasma techniques, both plasma activation and grafting/polymerization will be included in the review and linked to the in-vitro/in-vivo response to these treatments. The literature review itself is preceded by a more general overview on cell communication, giving useful insights on how surface modification strategies should be developed.

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Section: Rapid Prototypingmentioning

confidence: 94%

Section: Rapid Prototypingmentioning

confidence: 99%

Plasma Science and Technology - Progress in Physical States and Chemical Reactions

Mieno¹

2016

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“…1), pore side length 0.5 mm were prepared using a Bioscaffolder device (Sys-Eng) as described previously [1][2][3].…”

Section: Methodsmentioning

confidence: 99%

“…porosity, pore size). However, poor cell attachment and proliferation on PCL necessitates surface modification, for example by plasma treatment [1], sometimes combined with covalent coupling of gelatin and fibronectin [2][3][4].…”

Section: Introductionmentioning

confidence: 99%

Pulsed laser deposition of magnesium-doped calcium phosphate coatings on porous polycaprolactone scaffolds produced by rapid prototyping

et al. 2015

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“…Numerous studies have been devoted to gain a basic understanding of cell‐material surface interactions, which is of great importance in tissue engineering and other biomedical applications . As a result, it has been found that surface properties including chemical composition, surface energy, wettability, roughness, and surface topography significantly affect the cell adhesion and growth at the surface of materials . However, due to the fact that the mentioned properties are not utterly independent, the elucidation of the sole effect of each property on the cell‐material interactions is a quite difficult task.…”

Section: Introductionmentioning

confidence: 99%

Investigation on surface properties of superhydrophobic nanocomposites based on polyvinyl chloride and correlation with cell adhesion behavior

Naeemabadi

Seyfi

Hejazi

et al. 2019

Polymers for Advanced Techs

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The main aim was to study the roles of structural homogeneity and superhydrophobicity on the adhesion of SW colon cancer cells on the surface of polyvinyl chloride (PVC) nanocomposites. Concurrent use of a proper nonsolvent (ethanol) and silica nanoparticles resulted in superhydrophobic behavior and also different surface structures. The effect of added‐ethanol content on the surface properties of PVC nanocomposites was also studied. The synergetic combination of silica and ethanol has led to the formation of a porous surface layer resulting in a considerable boost in the hydrophobic behavior. The scanning electron microscopy, roughness, and X‐ray photoelectron spectroscopy (XPS) analysis results were all in total agreement indicating the substantial change in surface morphology, topography, and composition once the ethanol content was increased to 50 vol.%. The surface structure was notably changed by the addition of polyhedral oligomeric silsesquioxanes (POSS) nanoparticles. It was found that the induced inhomogeneity as a result of POSS addition had an adverse effect on the surface properties. In conclusion, superhydrophobicity could be regarded as a prerequisite for achieving cell‐repellent behavior, but it cannot guarantee a cell repellent surface especially if the surface layer possesses structural inhomogeneity.

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Improved cell adhesion to flat and porous plasma-treated poly-ε-caprolactone samples

Cited by 33 publications

References 22 publications

Plasma Science and Technology - Progress in Physical States and Chemical Reactions

Plasma Science and Technology - Progress in Physical States and Chemical Reactions

Pulsed laser deposition of magnesium-doped calcium phosphate coatings on porous polycaprolactone scaffolds produced by rapid prototyping

Investigation on surface properties of superhydrophobic nanocomposites based on polyvinyl chloride and correlation with cell adhesion behavior

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