Imported cases of chikungunya in metropolitan France: update to June 2006

Krastinova, Evguenia; Quatresous, I.; Tarantola, Arnaud

doi:10.2807/esw.11.34.03030-en

Cited by 24 publications

(27 citation statements)

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“…During 2006, numerous imported cases of chikungunya fever were diagnosed among travelers returning from Réunion, Seychelles, Mauritius, Madagascar, and India (31,33 ). A total of 766 imported cases of chikungunya have been identified in mainland France (i.e., excluding overseas departments and territories) since the beginning of the Indian Ocean outbreak (34 ). Because A. albopictus has already been introduced into several European countries (35)(36)(37), autochthonous CHIKV transmission is theoretically possible but has not been reported to date (33 ).…”

Section: Discussionmentioning

confidence: 99%

Development of a Sensitive Real-Time Reverse Transcriptase PCR Assay with an Internal Control to Detect and Quantify Chikungunya Virus

Laurent¹,

Roux²,

Grivard³

et al. 2007

Clinical Chemistry

118

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Background:The chikungunya virus (CHIKV; Alphavirus, Togaviridae) has emerged in the south Western Indian Ocean since early 2005. A major outbreak of CHIKV infection occurred in Réunion Island, where the virus is transmitted by Aedes albopictus mosquitoes. Facing an outbreak of unprecedented magnitude, we developed a rapid, sensitive, and reliable assay for the detection and quantification of CHIKV in plasma samples. Methods: A dual-color TaqMan 1-step reverse transcriptase PCR assay was developed in a LightCycler 2.0 system. A coextracted and coamplified chimerical RNA sequence was used as an internal control (IC) to eliminate false-negative results. The CHIKV-specific and IC probes were labeled with 6-carboxyfluorescein (530 nm) and the wide span dye DYXL (705 nm), respectively, eliminating the need for color compensation. A synthetic RNA was used as an external calibrator for CHIKV absolute quantification. Results: The detection limit was 350 copies/mL (3 copies/capillary). A further improvement to ϳ40 copies/mL was obtained by use of a larger volume of plasma. The assay specificity was confirmed in vitro and in silico. CHIKV in 343 patients was present at viral loads >10

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Section: Discussionmentioning

confidence: 99%

Development of a Sensitive Real-Time Reverse Transcriptase PCR Assay with an Internal Control to Detect and Quantify Chikungunya Virus

Laurent¹,

Roux²,

Grivard³

et al. 2007

Clinical Chemistry

118

View full text Add to dashboard Cite

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“…Consequently, in 2005 and2006, especially mainland France (Cordel et al 2006, Krastinova et al 2006), but also other European nations (Depoortere and Coulombier 2006), reported a sudden increase in imported CHIKV infections. The need for CHIKV surveillance in Europe was driven home by the autochthonous outbreak of CHIKV infections in central Italy in 2007 (Rezza et al 2007, Angelini et al 2008).…”

Section: Introductionmentioning

confidence: 99%

Trends in Imported Chikungunya Virus Infections in Germany, 2006–2009

Frank

Schöneberg

Stark

2011

Vector-Borne and Zoonotic Diseases

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“…9). For example, between 2005 and 2006, >800 infected persons returning from epidemic locations were identified in France (Krastinova et al, 2006) and 35 in the US (Lanciotti et al, 2007). …”

Section: Chikungunya Virusmentioning

confidence: 99%

Alphaviruses: Population genetics and determinants of emergence

et al. 2012

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Alphaviruses are responsible for several medically important emerging diseases and are also significant veterinary pathogens. Due to the aerosol infectivity of some alphaviruses and their ability to cause severe, sometimes fatal neurologic diseases, they are also of biodefense importance. This review discusses the ecology, epidemiology and molecular virology of the alphaviruses, then focuses on three of the most important members of the genus: Venezuelan and eastern equine encephalitis and chikungunya viruses, with emphasis on their genetics and emergence mechanisms, and how current knowledge as well as gaps influence our ability to detect and determine the source of both natural outbreaks and potential use for bioterrorism. This article is one of a series in Antiviral Research on the genetic diversity of emerging viruses.

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Imported cases of chikungunya in metropolitan France: update to June 2006

Abstract: We report a situation update of imported chinkungunya infections in metropolitan France (the part of France that is in Europe, including the Mediterranean island of Corsica), from April 2005 to June 2006

Cited by 24 publications

References 0 publications

Development of a Sensitive Real-Time Reverse Transcriptase PCR Assay with an Internal Control to Detect and Quantify Chikungunya Virus

Development of a Sensitive Real-Time Reverse Transcriptase PCR Assay with an Internal Control to Detect and Quantify Chikungunya Virus

Trends in Imported Chikungunya Virus Infections in Germany, 2006–2009

Alphaviruses: Population genetics and determinants of emergence

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