Important Concepts In Systems And Cybernetics

Angiotensin-Converting Enzyme 2, Feedback Systems, and COVID-19

“…13 This loss of control can be signaled downstream via the AT 1 receptor, with dysregulation and devastating downstream consequences. 13,14 Reciprocal inhibitory pathways, in certain situations (eg, hypoxia), can form positive feedback loops that can shift the balance between the adverse and protective axes. 12…”

“…That something is only there if the positive and negative feedbacks are in balance, not if stagnant or failed. 14 Conservation of molecular structure across phylogenetic branches suggests that the sequence had or has an important functions, 52 which may be unrelated to its function in mammals and which may remain elusive to us. Prolactin and related growth hormone, for example, are thought to have expanded, with their receptor family, by duplication, with the various forms filling functions as diverse as milk production, development, and metabolism.…”

“…From Future Ready: How to Master Business Forecasting 14 A stable negative feedback system can change to act as an unstable positive feedback loop if the timing of response exceeds the rate of disturbance for which the system was designed. 14 (For an introduction to feedback loops, see references 2, 58, 59, and 64.)…”

“…From Future Ready: How to Master Business Forecasting 14 A stable negative feedback system can change to act as an unstable positive feedback loop if the timing of response exceeds the rate of disturbance for which the system was designed. 14 (For an introduction to feedback loops, see references 2, 58, 59, and 64.) In the mid 1800s, J.C. Maxwell realized that this could explain a major contemporary issue-why steam locomotives with centrifugal governors had a tendency to explode.…”