Importance of loneliness in behavioral and psychological symptoms of dementia

Sun, Weiyi; Matsuoka, Teruyuki; Oba, Hikaru; Narumoto, Jin

doi:10.1002/gps.5450

Cited by 18 publications

(30 citation statements)

References 29 publications

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“…Social isolation might cause the feeling of loneliness, which can exacerbate behavior alterations. These conclusions align with those found in a very recent work, which assessed the NPI and the revised University of California at Los Angeles (UCLA) loneliness scale [ 34 ]. The revised UCLA loneliness scale score was not significantly associated with age, education, Mini-Mental state examination score, gender, physical impairments and marital status.…”

Section: Discussionsupporting

confidence: 91%

COVID-19 Lockdown Effect on Not Institutionalized Patients with Dementia and Caregivers

et al. 2021

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SARS-COV-2 is a severe medical condition. Old patients are very vulnerable, but they have been studied only as institutionalized patients. During the lock-down, little attention is dedicated to old, demented patients who lived at home. This study wants to examine their behavioral reactions by video-phone follow-up. We conducted a longitudinal study in subcortical vascular dementia (sVAD) patients. We enrolled 221 sVAD, not institutionalized patients. We divided sVAD patients into low-medium grade sVAD (A) and severe sVAD (B), based on neuroimaging severity degree and executive alterations. At baseline, at the end of lock-down, and two months later, global behavioral symptoms were recorded for each patient. We found significantly higher scores of general behavioral deterioration, anxiety, delusions, hallucinations and apathy after controlling for sVAD severity. The direct consequence was a drastic increment of psychotropic drugs prescribed and employed during the lock-down. Moreover, caregivers’ stress has been evaluated, together with their anxiety and depression levels. During the lock-down, their scores increased and reflected a severe worsening of their behavior. Our data demonstrate that social isolation induces a severe perception of loneliness and abandonment; these fears can exacerbate behavior disturbances in old-aged frail persons. Thus, these can be considered as indirect victims of SARS-COV-2.

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Section: Discussionsupporting

confidence: 91%

COVID-19 Lockdown Effect on Not Institutionalized Patients with Dementia and Caregivers

et al. 2021

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“…Victor et al ( 39 ) found that 30.1% of 1,547 dementia patients reported feeling moderately lonely. Loneliness is also a risk factor for psychiatric behavioral problems in patients with dementia ( 40 ). Chinese scholars have also conducted studies on the psychological problems of dementia patients and their caregivers ( 41 , 42 ), but have not yet intervened using the Montessori approach.…”

Section: Discussionmentioning

confidence: 99%

Research Trends and Hotspots on Montessori Intervention in Patients With Dementia From 2000 to 2021: A Bibliometric Analysis

Zhou

Sun

et al. 2021

Front. Psychiatry

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Background: Patients with dementia experience a variety of neuropsychiatric symptoms and behavioral disturbances. The Montessori method is a type of non-pharmacological intervention to care for people with dementia. However, there are few bibliometric studies on the application of Montessori methods. We aimed to analyze the hotspots and trends of research on the application of Montessori methods to the care of dementia patients.Methods: Microsoft Office Excel, Co-Occurrence 9.9, and CiteSpace were used to analyze the articles on Montessori intervention in patients with dementia from 2000 to 2021 in China National Knowledge Infrastructure, Wanfang, China Science and Technology Journal Database, Web of Science core collection database, PubMed, and Scopus.Results: A total of 23 Chinese language publications and 113 English language publications were included. The number of English language publications was on the rise, while the number of Chinese language publications was low. There are many issuing institutions which published articles in this field, mostly concentrated in universities. English language publication sources were more than Chinese language publication sources. The hot research topic in Chinese language publications and English language publications was the care of agitated behavior of dementia patients based on the Montessori method. The psychological problems of dementia patients are likely to become a hot issue of concern for scholars in Chinese. There will be a lot of research focusing on dementia patients and their family caregivers in this field.Conclusion: The bibliometric and visualization analysis helps us understand the current research status and hotspots of Montessori intervention in dementia patients in Chinese language publications and English language publications.

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“…Although longitudinal studies cannot establish causal directionality, these studies consistently demonstrate an association between loneliness and subsequent cognitive decline [ 63 ]. Loneliness has reliably been associated with increased risk of Alzheimer’s disease and related dementias [ 66 , 67 , 68 , 69 ], in addition to worse behavioral and psychological symptoms of dementia [ 70 ]. Moreover, this increase in dementia risk seems to be most relevant for individuals with persistent loneliness compared to individuals with transient loneliness in whom dementia risk remains unchanged [ 67 ].…”

Section: Discussionmentioning

confidence: 99%

The Long-Term Public Health Impact of Social Distancing on Brain Health: Topical Review

Kumar

Salinas

2021

IJERPH

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Social distancing has been a critical public health measure for the COVID-19 pandemic, yet a long history of research strongly suggests that loneliness and social isolation play a major role in several cognitive health issues. What is the true severity and extent of risks involved and what are potential approaches to balance these competing risks? This review aimed to summarize the neurological context of social isolation and loneliness in population health and the long-term effects of social distancing as it relates to neurocognitive aging, health, and Alzheimer’s disease and related dementias. The full scope of the underlying causal mechanisms of social isolation and loneliness in humans remains unclear partly because its study is not amenable to randomized controlled trials; however, there are many detailed experimental and observational studies that may provide a hypothesis-generating theoretical framework to better understand the pathophysiology and underlying neurobiology. To address these challenges and inform future studies, we conducted a topical review of extant literature investigating associations of social isolation and loneliness with relevant biological, cognitive, and psychosocial outcomes, and provide recommendations on how to approach the need to fill key knowledge gaps in this important area of research.

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Importance of loneliness in behavioral and psychological symptoms of dementia

Cited by 18 publications

References 29 publications

COVID-19 Lockdown Effect on Not Institutionalized Patients with Dementia and Caregivers

COVID-19 Lockdown Effect on Not Institutionalized Patients with Dementia and Caregivers

Research Trends and Hotspots on Montessori Intervention in Patients With Dementia From 2000 to 2021: A Bibliometric Analysis

The Long-Term Public Health Impact of Social Distancing on Brain Health: Topical Review

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