Abstract:Introduction: Ischemic stroke is account for most of the mortality and morbidity cases around the World. Paraoxonase-1 (PON1) is a significant candidate gene for ischemic stroke because of its function against atherosclerosis. Methods: We studied two common polymorphisms (Q192R [rs662] and L55M [rs854560]) of PON1 gene using PCR-based RFLP assay. Overall, 107 patients diagnosed as acute ischemic stroke and 99 healthy controls were enrolled in the present study. We also carried out a meta-analysis containing 3 … Show more
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