“…They are associated with white matter lesions,12,13 silent brain infarction,14 a high prevalence of stroke,15,16 worse prognosis, in terms of both short- and long-term morbidity and mortality,9,10 and recurrence of vascular events (stroke, myocardial infarction, heart failure) 10. Pathologic renal findings are also described in young patients affected with stroke, mainly related to hypertensive cardiopathy, nephroangiosclerosis, and chronic pyelonephritis 17. Lastly, renal dysfunction is related to cognitive impairment and dementia 18–21…”