2022
DOI: 10.3390/diagnostics12040948
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Implications of Myocardial Bridge on Coronary Atherosclerosis and Survival

Abstract: Background: In this study, we aimed to describe the impact of MBs on atherosclerosis and survival, in patients with coronary artery disease (CAD). Methods: We retrospectively studied 1920 consecutive patients who underwent conventional coronary angiography for suspected CAD. Atherosclerotic load (AL), defined as the sum of degrees of stenosis, and general atherosclerotic load (GAL), representing the sum of AL, were compared between patients with MB and a control group without MB; patients in these groups were … Show more

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Cited by 6 publications
(14 citation statements)
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“…MB milking might also cause ischemia by an 'branch steal' or 'intramural steal' mechanism linked to decreased perfusion pressure of the blood suction and septal branches. In some studies, MB was also shown to be a protective (23,24) or predictive (25)(26)(27) factor of atherosclerosis. Especially, proximal segment of the bridge was considered to be a major risk factor of atherosclerosis (23,24,26,27).…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…MB milking might also cause ischemia by an 'branch steal' or 'intramural steal' mechanism linked to decreased perfusion pressure of the blood suction and septal branches. In some studies, MB was also shown to be a protective (23,24) or predictive (25)(26)(27) factor of atherosclerosis. Especially, proximal segment of the bridge was considered to be a major risk factor of atherosclerosis (23,24,26,27).…”
Section: Discussionmentioning
confidence: 99%
“…In some studies, MB was also shown to be a protective (23,24) or predictive (25)(26)(27) factor of atherosclerosis. Especially, proximal segment of the bridge was considered to be a major risk factor of atherosclerosis (23,24,26,27). Overall, MB related symptoms and complications are observed to be highly dependent on various clinical and pathophysiological factors such as age of the patient, degree of systolic narrowing, hear rate or diastolic perfusion time, intrinsic and extrinsic factors (coronary vasoconstriction, sympathetically driven myocardial contraction, transmural perfusion gradients, diastolic flow, arterial/myocardial compression, and aortic pressure), biochemical factors (led to intimal injuries developing into coronary dissection, vasospasticity, and plaque vulnerability/thrombosis), number of tunneled segments, depth of tunneled artery, presence of coronary atherosclerosis, left ventricle (LV) hypertrophy, and the length of the tunneled artery or location of the bridge (21).…”
Section: Discussionmentioning
confidence: 99%
“…An important section of this Special Issue is dedicated to the implications of myocardial bridge in patients with CAD [ 5 ]. The myocardial bridge (MB) represents the muscle fibres that abnormally overlie the intramyocardial passage of an epicardial coronary artery, which consequently becomes tunnelled in its path beneath them.…”
mentioning
confidence: 99%
“…Although few isolated MBs have a clinical expression, myocardial ischemia induced by isolated MBs may manifest in significant clinical forms, such as silent ischemia, stable angina, acute coronary syndromes, arrhythmias, and even sudden cardiac death. Darabont et al [ 5 ] studied 1920 consecutive patients who underwent coronary angiographyand identified 76 patients with myocardial bridging. Interestingly, the presence of MB on LAD is not an additional risk factor for coronary atherosclerosis.…”
mentioning
confidence: 99%
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