Abstract:Background
We performed a secondary analysis of ACIS study to determine if synchronous versus metachronous metastatic presentation has any association with survival and treatment response to dual androgen receptor axis‐targeted therapy (ARAT) in docetaxel naïve metastatic castrate resistant prostate cancer (mCRPC).
Methodology
In this phase III randomized controlled trial, docetaxel naïve mCRPC patients were randomized to either apalutamide or placebo combined with abiraterone and prednisone. Multivariable Cox… Show more
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