Implications of Early Pregnancy Obesity on Maternal, Fetal and Neonatal Health: Retrospective cohort study from Oman

Abstract

abstract:Objectives: This study aimed to determine the prevalence of early pregnancy obesity among Omani women and to review maternal antenatal complications, intrapartum and postpartum events and neonatal complications among such women in comparison to women of normal weight. Methods: This retrospective cohort study included 2,652 pregnant Omani women who delivered at the Royal Hospital, Muscat, Oman, between November 2011 and April 2012. The patients' electronic medical records were reviewed for antenatal, intrapartum and postpartum data. Body mass index was measured during the first trimester (≤12 gestational weeks) and classified according to the World Health Organization categories. Maternal and neonatal complications were compared between obese women and those of normal weight. Obstetric outcomes in uncomplicated pregnancies were also compared. Results: In the study cohort, there were 901 (34%) obese women and 912 (34.4%) women of normal weight; of these, 440 (48.8%) and 672 (73.7%) had uncomplicated pregnancies, respectively. Obese women had a significantly increased incidence of gestational diabetes (relative risk [RR]: 2.23; 95% confidence interval [CI]: 1.70-2.92; P <0.01), gestational hypertension (RR: 3.04; 95% CI: 1.63-5.65; P <0.01), Caesarean delivery (RR: 1.48; 95% CI: 1.08-2.03; P <0.01), postpartum haemorrhage (RR: 2.10; 95% CI: 1.11-4.10; P = 0.01) and fetal macrosomia (RR: 2.71; 95% CI: 1.21-6.09; P <0.01). Conclusion: Approximately one-third of the studied Omani women were obese. These women had a significantly increased risk of various maternal antenatal complications, intrapartum and postpartum events and neonatal complications. Keywords

Maternal and birth cohort studies in the Gulf Cooperation Council countries: a systematic review and meta-analysis

“…The size of the cohorts ranged from 23 pregnant women with a known diagnosis of idiopathic thrombocytopenic in Saudi Arabia [62] to 158,006 delivering mothers in Kuwait [81]. Majority (64.2%) of the cohort studies were in Saudi Arabia [25][26][27]40 [54,55,78,[102][103][104], and one (1.2%) in Bahrain [22] (see Additional file 3: Table S2).…”

“…Thirty-four cohort studies (42.0%) were identified as a prospective design (19 in [81], and three in the UAE). Fiftytwo (64.2%) cohort studies enrolled pregnant mothers at varying stages of their pregnancy with different characteristics such as diabetic and non-diabetic mothers [26,67], obesity [42,47,54], singleton [41,48,99] or triplet pregnancies [91], teenage women [112], multipara women [82,86,98], and women with systemic lupus erythematosus (SLE) [27]. Eight studies (9.9%) enrolled pregnant mothers at varying stages after delivery [24,49,58,59,81,84,88,99].…”

“…Environmental exposures included smoking and secondhand smoking [49,56], and all six studies on anthropometric measures were on BMI (Table 1 and see Additional file 3: Table S2). [47,50,53,54,83,111,113], and maternal anemia in three cohort studies [50,104,113]. Postpartum depression was explored in only one prospective cohort study in the UAE [76].…”

The Influence of Preeclampsia, Advanced Maternal Age and Maternal Obesity in Neonatal Outcomes Among Women with Gestational Diabetes

“…30.0 kg/m2, is increasing over time. 5,12,18 Pregestational BMI is a risk factor for the development of maternal and perinatal complications. 24,27 In the clinical practice, obesity and gestational diabetes commonly coexist and it is controversial which one the two conditions (gestational diabetes or maternal obesity) is more strongly associated with risk for adverse maternal and neonatal outcomes.…”

Maternal obesity and intrapartum obstetric complications among pregnant women: Retrospective cohort analysis from medical birth registry in Northern Tanzania

“…Previous studies have reported on the association between higher body mass index (BMI) and increased risk of adverse maternal outcomes and obstetric intrapartum complications . These complications include hypertensive disorders in pregnancy such as eclampsia/preeclampsia, gestational diabetes mellitus (GDM), thromboembolic disorders, postpartum haemorrhage (PPH), and maternal deaths as well as services indicative of complications include induction of labour and caesarean delivery . In addition, the evidence from 14 countries in SSA shows that obesity in pregnancy is associated with increased risks of adverse labour, child, and maternal outcomes …”