Implication of Metrizamide Myelography

Confusion, Dysphasia, and Asterixis Following Metrizamide Myelography

“…Despite these advantages, significant side effects have occurred. These side effects have included transient hallucinations (Eldevik, Nakken, et al, 1978;Grainger, Kendall, et al, 1976;Sortland, Lundervold, et al, 1977), hyperacusis (Grainger, Kendall, et al, 1976), seizures (Sortland, Lundervold, et al, 1977;Lundervold and Sortland, 1977;Nickel and Salem, 1977), significant electroencephalographic (EEG) abnormalities (Sortland, Lundervold, et al, 1977;Lundervold and Sortland, 1977;Skalpe, Tabergsen, et al, 1973;Kaada, 1977;Skalpe, 1975Skalpe, , 1977, areflexia (Buruma and Hekster, 1977), cerebrospinal fluid ( C S F ) pleocytosis (Grainger, Kendall, et al, 1976;Skalpe, 1977), nausea, vomiting (Eldevik, Nakken, et al, 1978;Grainger, Kendall, et al, 1976;Nickel and Salem, 1977), and confusion (Eldevik, Nakken, et al, 1978;Sortland, Lundervold, et al, 1977;Koerner, 1979). We report a patient in whom a prolonged confusional state, dysphasie speech, includ-ing echolalia and perseveration, and striking asterixis followed metrizamide myelography.…”