Implication of central neurohypophyseal hormone receptor-mediated action in the timing of reproductive events: evidence from novel observations on the effect of a vasotocin analogue on singing behaviour of the canary

Kloet, E. Ronald de; Elands, Jack; Voorhuis, Dorothy A.M.

doi:10.1016/0167-0115(93)90187-d

Cited by 15 publications

(5 citation statements)

References 15 publications

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“…Song was measured several weeks later, and was found to increase or decrease depending upon the season, suggesting that VT may mediate seasonal transitions in song behavior (Voorhuis et al, 1991; De Kloet et al, 1993). However, immediate effects of VT on singing appear to be restricted to agonistic song types (Maney et al, 1997; Goodson, 1998a), as summarized in the previous section, and multiple experiments in male zebra finches demonstrate that directed courtship singing is not influenced by central infusions of VT, MT, or a diversity of nonapeptide receptor antagonists (Goodson and Adkins-Regan, 1999; Goodson et al, 2004; Kabelik et al, 2009).…”

Section: Nonapeptide Modulation Of Female-directed Song and Sexual Bementioning

confidence: 99%

Evolving nonapeptide mechanisms of gregariousness and social diversity in birds

Goodson

Kelly

Kingsbury

2012

Hormones and Behavior

124

101

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Of the major vertebrate taxa, Class Aves is the most extensively studied in relation to the evolution of social systems and behavior, largely because birds exhibit an incomparable balance of tractability, diversity, and cognitive complexity. In addition, like humans, most bird species are socially monogamous, exhibit biparental care, and conduct most of their social interactions through auditory and visual modalities. These qualities make birds attractive as research subjects, and also make them valuable for comparative studies of neuroendocrine mechanisms. This value has become increasingly apparent as more and more evidence shows that social behavior circuits of the basal forebrain and midbrain are deeply conserved (from an evolutionary perspective), and particularly similar in birds and mammals. Among the strongest similarities are the basic structures and functions of avian and mammalian nonapeptide systems, which include mesotocin (MT) and arginine vasotocin (VT) systems in birds, and the homologous oxytocin (OT) and vasopressin (VP) systems, respectively, in mammals. We here summarize these basic properties, and then describe a research program that has leveraged the social diversity of estrildid finches to gain insights into the nonapeptide mechanisms of grouping, a behavioral dimension that is not experimentally tractable in most other taxa. These studies have used five monogamous, biparental finch species that exhibit group sizes ranging from territorial male-female pairs to large flocks containing hundreds or thousands of birds. The results provide novel insights into the history of nonapeptide functions in amniote vertebrates, and yield remarkable clarity on the nonapeptide biology of dinosaurs and ancient mammals.

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Section: Nonapeptide Modulation Of Female-directed Song and Sexual Bementioning

confidence: 99%

Evolving nonapeptide mechanisms of gregariousness and social diversity in birds

Goodson

Kelly

Kingsbury

2012

Hormones and Behavior

124

101

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“…Most vertebrate classes possess the ancestral nine amino acid peptide form, arginine vasotocin (AVT; AVP has a phenylalanine substitution of isoleucine in position 3) ( 3 ). Originally identified for its role in osmoregulation, cardiovascular function, and stress hormone release ( 4 – 6 ), AVP/T has also been shown to play a key role in modulating social behavior such as courtship and aggressive behavior in fish ( 7 – 9 ), amphibians ( 10 – 12 ), birds ( 13 – 16 ), and in mammals ( 17 – 19 ). AVP/T has also been shown to modulate territoriality and space use [reviewed in Ref.…”

Section: Introductionmentioning

confidence: 99%

Arginine Vasotocin Preprohormone Is Expressed in Surprising Regions of the Teleost Forebrain

et al. 2017

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Nonapeptides play a fundamental role in the regulation of social behavior, among numerous other functions. In particular, arginine vasopressin and its non-mammalian homolog, arginine vasotocin (AVT), have been implicated in regulating affiliative, reproductive, and aggressive behavior in many vertebrate species. Where these nonapeptides are synthesized in the brain has been studied extensively in most vertebrate lineages. While several hypothalamic and forebrain populations of vasopressinergic neurons have been described in amniotes, the consensus suggests that the expression of AVT in the brain of teleost fish is limited to the hypothalamus, specifically the preoptic area (POA) and the anterior tuberal nucleus (putative homolog of the mammalian ventromedial hypothalamus). However, as most studies in teleosts have focused on the POA, there may be an ascertainment bias. Here, we revisit the distribution of AVT preprohormone mRNA across the dorsal and ventral telencephalon of a highly social African cichlid fish. We first use in situ hybridization to map the distribution of AVT preprohormone mRNA across the telencephalon. We then use quantitative real-time polymerase chain reaction to assay AVT expression in the dorsomedial telencephalon, the putative homolog of the mammalian basolateral amygdala. We find evidence for AVT preprohormone mRNA in regions previously not associated with the expression of this nonapeptide, including the putative homologs of the mammalian extended amygdala, hippocampus, striatum, and septum. In addition, AVT preprohormone mRNA expression within the basolateral amygdala homolog differs across social contexts, suggesting a possible role in behavioral regulation. We conclude that the surprising presence of AVT preprohormone mRNA within dorsal and medial telencephalic regions warrants a closer examination of possible AVT synthesis locations in teleost fish, and that these may be more similar to what is observed in mammals and birds.

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“…The functional roles of their non-mammalian counterparts vasotocin and isotocin/mesotocin are less well defined. However, recent binding, in situ hybridization, and physiological studies suggest that these peptides mediate a number of diverse activities in lower vertebrates including reproductive, renal, cardiovascular, metabolic, and hydroosmotic functions; in addition, they may play a role in urine excretion and in the modulation of neurotransmission [1][2][3][4][5][6][7][8][9][10]. This broad range of physiological effects and the observation of diverse signal transduction pathways point to the existence of a number of nonapeptide receptor subtypes in non-mammalian species.…”

Section: Introductionmentioning

confidence: 99%

Teleost isotocin receptor: structure, functional expression, mRNA distribution and phylogeny

et al. 1995

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A cDNA encoding a receptor for the oxytocin-related peptide isotocin has been identified by screening a lambda gtll library constructed from poly(A) ÷ RNA of the hypothalamic region of the teleost Catostomus commersonL The probe used was obtained by PCR amplification of white sucker genomic DNA using degenerate primers based on conserved sequences in the mammalian receptor counterparts. The full-length eDNA specifies a polypeptide of 390 amino acid residues that displays the typical hydrophobicity profile of a seven transmembrane domain receptor and which exhibits greatest similarity to mammalian oxytocin receptors. Oocytes that express the cloned receptor respond to the application of isotocin by an induction of membrane chloride currents indicating that it is coupled to the inositol phosphate/calcium pathway. The isotocin receptor (ITR) can also be activated by vasotocin, mesotocin, oxytocin and Arg-vasopressin, although these have lower potencies than isotocin. ITRencoding mRNA has been detected in brain, intestine, bladder, skeletal muscle, lateral line, gills and kidney indicating that this receptor may mediate a variety of physiological functions.

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Implication of central neurohypophyseal hormone receptor-mediated action in the timing of reproductive events: evidence from novel observations on the effect of a vasotocin analogue on singing behaviour of the canary

Cited by 15 publications

References 15 publications

Evolving nonapeptide mechanisms of gregariousness and social diversity in birds

Evolving nonapeptide mechanisms of gregariousness and social diversity in birds

Arginine Vasotocin Preprohormone Is Expressed in Surprising Regions of the Teleost Forebrain

Teleost isotocin receptor: structure, functional expression, mRNA distribution and phylogeny

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