2009
DOI: 10.2967/jnumed.109.068759
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Implementation of an Automated Respiratory Amplitude Gating Technique for PET/CT: Clinical Evaluation

Abstract: Amplitude gating techniques have recently been shown to be better at suppressing respiratory motion artifacts than phase gating. However, most commercial PET/CT scanners are equipped with phase gating capabilities only. The objective of this article was to propose and evaluate using patient studies an automated respiratory amplitude gating technique that could be implemented on current whole-body PET/CT scanners. A primary design feature of the proposed technique is to automatically match the respiratory ampli… Show more

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Cited by 65 publications
(47 citation statements)
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“…Second, it has been demonstrated that phasebased respiratory gating is less effective than amplitudebased gating, especially in patients with irregular respiratory cycles [13]. Despite this knowledge, phase-based methods of gating remain the most widely investigated in cancer research [15], as in the current study. In addition, six respiratory gates have been suggested as the optimal number in phase-based respiratory gating [38], while we used only four phase gates in order to limit image noise.…”
Section: A Salavati Et Al: Partial Volume Effect Correction Vs 4d mentioning
confidence: 78%
See 1 more Smart Citation
“…Second, it has been demonstrated that phasebased respiratory gating is less effective than amplitudebased gating, especially in patients with irregular respiratory cycles [13]. Despite this knowledge, phase-based methods of gating remain the most widely investigated in cancer research [15], as in the current study. In addition, six respiratory gates have been suggested as the optimal number in phase-based respiratory gating [38], while we used only four phase gates in order to limit image noise.…”
Section: A Salavati Et Al: Partial Volume Effect Correction Vs 4d mentioning
confidence: 78%
“…In 2002, Nehmeh et al were the first to perform respiratory gating for PET scanning in clinical setting and found that respiratory gating decreases total lesion volume and increases measured SUV compared to non-gated images [14]. Gating has also been reported to improve the diagnosis of malignant lung lesions and the evaluation of response to radiation treatment [15][16][17][18].…”
Section: Introductionmentioning
confidence: 99%
“…Several authors have shown that amplitude-based approaches are most robust in the case of irregular breathing patterns compared with phase-based gating approaches. [33][34][35] The Q.Freeze software does not propose any amplitude sampling and only proposes a time sampling.…”
Section: Patient Studymentioning
confidence: 99%
“…All spheres were filled with identical activity concentration of 42.2 kBq/cc (SUV = 15) of 18 F except for the 47 mm sphere which had half of this concentration. The largest sphere had half the concentration in order to reduce the total count rate from the phantom and prevent count rate effects from impacting the image quality.…”
Section: Iib 4d Pet/ct Phantom Studymentioning
confidence: 99%
“…The key to a good 4D scan is a highly stable breathing pattern that enables accurate data binning. Amplitude based binning methods 17,18 have been shown to give better results than phase binning in situations when there are breathing period or amplitude variations but is not widely available commercially. Phase binning is particularly prone to respiratory signal baseline drift and amplitude irregularities which lead to binning errors.…”
Section: Introductionmentioning
confidence: 99%