“…In understanding that OUD is indeed a brain disorder and a chronic life-time struggle—like diabetes—involving physiological, psychological and spiritual aspects, frontline modalities could benefit by the incorporation of alternatives like rTMS [ 12 , 13 ]. There is continual benefit from the use of both Cognitive Behavioral Therapy, Mindfulness, and other psychological approaches such as trauma therapy and even Unilateral Transcranial Photo biomodulation [ 14 , 15 , 16 ]. Certainly, there is good evidence that religiosity and spirituality have positive neurochemical benefits at the brain reward circuitry resulting in significantly reduced relapse [ 17 , 18 , 19 , 20 , 21 , 22 , 23 , 24 , 25 , 26 , 27 , 28 , 29 , 30 ].…”