Implantable contact lens for high myopia

Uusitalo, Risto; Aine, Esko; Sen, Nida H; Laatikainen, Leila

doi:10.1016/s0886-3350(01)01218-4

Cited by 139 publications

(77 citation statements)

References 23 publications

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“…[1][2][3][4][5][6][7][8][9] This surgical procedure may have advantages over laser in situ keratomileusis (LASIK) because it is not only highly predictable but also reversible. It may also have advantages over refractive lens exchange because the crystalline lens, which plays a major role in accommodative function, especially in younger patients, remains untouched.…”

Section: Introductionmentioning

confidence: 99%

Clinical outcomes and patient satisfaction after Visian Implantable Collamer Lens removal and phacoemulsification with intraocular lens implantation in eyes with induced cataract

Kamiya

Shimizu

Igarashi

et al. 2009

Eye

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Purpose To assess the clinical outcomes and patient satisfaction after simultaneous Implantable Collamer Lens (ICL) removal and phacoemulsification with intraocular lens (IOL) implantation in ICL-implanted eyes with developing cataracts. Methods We retrospectively reviewed the clinical charts of 10 eyes of eight patients who developed significant cataract after ICL implantation. Patient age was 47.2 ± 5.9 (mean ± SD) years (range, 37-57 years). We determined visual acuity (log MAR), manifest refraction, endothelial cell density, and subjective satisfaction with visual outcomes measured using a visual analogue scale, that ranged from 0 (very dissatisfied) to 10 (very satisfied), before and 3 months after cataract surgery. Results Log MAR best spectacle-corrected visual acuity was significantly improved from 0.19±0.30 preoperatively to À0.06±0.07 postoperatively (P ¼ 0.007, Wilcoxon signedrank test). Eight (80%) and nine (90%) of the 10 eyes were within 0.5 D (diopter) and 1.0 D of the targeted correction, respectively. The endothelial cell density was 2584.9 ± 266.2 cells/mm 2 preoperatively, and 2340.1±269.7 cells/mm 2 postoperatively. The overall satisfaction with visual outcomes was scored 1.8±1.1 (range: 0-3) preoperatively, and 7.9±1.4 (range: 6-10) postoperatively. No vision-threatening complications were seen throughout the follow-up period. Conclusions Simultaneous ICL removal and phacoemulsification with IOL implantation was safe and effective with predictable refractive results, and thus yielded a high level of patient satisfaction with ICL-induced cataract treatment.

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Section: Introductionmentioning

confidence: 99%

Clinical outcomes and patient satisfaction after Visian Implantable Collamer Lens removal and phacoemulsification with intraocular lens implantation in eyes with induced cataract

Kamiya

Shimizu

Igarashi

et al. 2009

Eye

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“…[1][2][3][4][5][6][7][8][9][10] This surgical procedure may have advantages over laser in situ keratomileusis (LASIK) because it is safer and more effective, and provides highly predictable and stable results, especially in the correction of high myopia. Moreover, the lens is removable and replaceable with another ICL, whereas, with LASIK, this cannot be done even when unexpected refractive outcomes occur after surgery.…”

Section: Introductionmentioning

confidence: 99%

Evaluation of pupil diameter after posterior chamber phakic intraocular lens implantation

Kamiya

Shimizu

Igarashi

et al. 2009

Eye

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Purpose To observe the changes of pupil size over time after Visian Implantable Collamer Lens (ICL) implantation. Patients and methods We retrospectively examined 30 eyes of 23 consecutive patients undergoing ICL implantation. We measured the entrance and real pupil diameters using a Hartmann-Shack aberrometer (KR-9000, Topcon, Tokyo, Japan) before and 1 day, 1 week, and 1, 3, 6, and 12 months after surgery. We also investigated its relationship with the amount of vaulting using slit-lamp microscopy 1 year postoperatively. Results The entrance pupil diameters were 6.24 ± 0.66 (mean ± standard deviation) mm preoperatively, and 5.53 ± 0.69, 6.18 ± 0.61, 6.21±0.80, 6.29±0.74, 6.23±0.76, and 6.40±0.70 mm, 1 day, 1 week, and 1, 3, 6, and 12 months postoperatively, respectively; and the respective real pupil diameters were 5.44 ± 0.55 mm preoperatively, and 4.95 ± 0.60, 5.53 ± 0.52, 5.55 ± 0.69, 5.63 ± 0.64, 5.57 ± 0.64, and 5.72 ± 0.60 mm, 1 day, 1 week, and 1, 3, 6, and 12 months postoperatively. Pupil diameters and the amount of vaulting were not significantly associated (Pearson correlation coefficient r ¼ 0.14, P ¼ 0.45 for entrance pupil, r ¼ 0.13, P ¼ 0.49 for real pupil). Conclusions Both pupil diameters decreased transiently 1 day after ICL implantation, but soon recovered to the preoperative level, indicating that intraoperative mechanical irritation of the uveal tissue and the early postoperative inflammatory response may induce transient decreases in pupil diameter, and that this surgical technique alone with appropriate ICL size selection probably induces no significant pupil diameter change.

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“…This refractive surgery technique consists of introducing an intraocular contact lens in the anterior chamber through a small incision in the corneal periphery, close to the limbus (Kamiya et al, 2010;Uusitalo et al, 2002). With this procedure the corneal neural network is preserved (Alfonso et al, 2013;Ali et al, 2014).…”

Section: Presence After Ocular Surface Surgerymentioning

confidence: 99%

The role of dinucleoside polyphosphates on the ocular surface and other eye structures

Carracedo

Crooke

Guzmán-Aránguez

et al. 2016

Progress in Retinal and Eye Research

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a b s t r a c tDinucleoside polyphosphates comprises a group of dinucleotides formed by two nucleosides linked by a variable number of phosphates, abbreviated NpnN (where n represents the number of phosphates). These compounds are naturally occurring substances present in tears, aqueous humour and in the retina. As the consequence of their presence, these dinucleotides contribute to many ocular physiological processes. On the ocular surface, dinucleoside polyphosphates can stimulate tear secretion, mucin release from goblet cells and they help epithelial wound healing by accelerating cell migration rate. These dinucleotides can also stimulate the presence of proteins known to protect the ocular surface against microorganisms, such as lysozyme and lactoferrin. One of the latest discoveries is the ability of some dinucleotides to facilitate the paracellular way on the cornea, therefore allowing the delivery of compounds, such as antiglaucomatous ones, more easily within the eye. The compound Ap 4 A has been described being abnormally elevated in patient's tears suffering of dry eye, Sjogren syndrome, congenital aniridia, or after refractive surgery, suggesting this molecule as biomarker for dry eye condition. At the intraocular level, some diadenosine polyphosphates are abnormally elevated in glaucoma patients, and this can be related to the stimulation of a P2Y 2 receptor that increases the chloride efflux and water movement in the ciliary epithelium. In the retina, the dinucleotide dCp 4 U, has been proven to be useful to help in the recovery of retinal detachments. Altogether, dinucleoside polyphosphates are a group of compounds which present relevant physiological actions but which also can perform promising therapeutic benefits.

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Implantable contact lens for high myopia

Abstract: At 1 year, ICL implantation had good visual and refractive results with excellent biocompatibility. Long-term follow-up is required to confirm that significant complications do not occur in most patients over time.

Cited by 139 publications

References 23 publications

Clinical outcomes and patient satisfaction after Visian Implantable Collamer Lens removal and phacoemulsification with intraocular lens implantation in eyes with induced cataract

Clinical outcomes and patient satisfaction after Visian Implantable Collamer Lens removal and phacoemulsification with intraocular lens implantation in eyes with induced cataract

Evaluation of pupil diameter after posterior chamber phakic intraocular lens implantation

The role of dinucleoside polyphosphates on the ocular surface and other eye structures

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