Implantable cardioverter defibrillator and survival after out-of-hospital cardiac arrest due to acute myocardial infarction in Denmark in the years 2001–2012, a nationwide study

Abstract

Cardioverter defibrillator implantation rates in patients surviving an myocardial infarction-out-of-hospital cardiac arrest increased from 14% to 19% over the period. Of the total patient population, 13% had implantation earlier than recommended by guidelines, presumably as primary prevention of sudden cardiac death. Acute PCI and arrest later in the study period (increase one year) were predictors of late cardioverter defibrillator implantation. Early cardioverter defibrillator implantation was significantly associated with a long-term survival benefit, later implantation was not.

Growth differentiation factor-15 is a predictive biomarker in primary ventricular fibrillation: The RUTI-STEMI-PVF study

“…27 The early implantation of a cardioverter defibrillator could be associated with long term survival benefit after out-of-hospital cardiac arrest due to MI. 28 New-generation biomarkers, such as GDF-15, measured with a state-of-the-art fully automated electrochemiluminescence assay, may support the clinician in risk stratification and provide for better patient allocation at discharge. Indeed, high GDF-15 may indicate a patient with a high risk for adverse events, requiring close monitoring by in-hospital staff or even heart failure specialists.…”

Analysis of correlation between heart failure in the early stage of acute myocardial infarction and serum pregnancy associated plasma protein-A, prealbumin, C-reactive protein, and brain natriuretic peptide levels

“…Through the analysis of relevant literature, it is found that serum pregnancy-associated plasma protein A (PAPP-A) was first found in pregnancy serum, and has subsequently been applied in obstetrics and gynecology research. In recent years, some studies have shown that PAPP-A directly promotes the occurrence and progression of atherosclerotic plaque (9)(10)(11)(12). Prealbumin (PAB), a kind of negative acute phase response protein that is often detected in clinical settings, is involved in the pathological process of many diseases through an inflammatory response mechanism.…”

An Evaluation of the Association between Quality of Life and Psychological Issues in Patients with Automated Implantable Cardioverter Defibrillator

“…12 In this respect, approximately 44% of patients experienced some degrees of shock anxiety, associated with cardiac fear, physical inactivity, and increased morbidity and mortality. 5 Additionally, survival after sudden cardiac arrest, 13 frequent hospitalizations, 14 and invasive electrophysiological examinations 15 result in patients' instability. 16 The most common feelings include negative feelings due to unpredictability of the number of shocks, 17 dependence on ICD, weak psychosocial adaptation, worries about one's status after cardiac arrest, depression, anger, and anxiety.…”