Impetigo herpetiformis with IL-36RN mutation successfully treated with secukinumab

Significance of IL36RN mutation analyses in the management of impetigo herpetiformis: A case report and review of published cases

“…[4][5][6][7][8][9][10][11][12] Among 10 IH patients of East Asian descent, seven had Summary of impetigo herpetiformis patients and IL36RN mutations…”

Recurrence of impetigo herpetiformis carrying compound heterozygous mutations in IL36RN after remission with secukinumab

“…1,2 So far, the clinical course after delivery has been reported in four patients with IL36RN mutations, 1,3-5 and one patient was reported to have long-term remission after discontinuing a total of six doses of secukinumab. 3 Following this report, in our case, secukinumab was discontinued after a total of six doses; however, the skin symptoms recurred approximately 1 year after the secukinumab withdrawal.…”

Pustular psoriasis of pregnancy: Clinical and genetic characteristics in a series of eight patients and review of the literature

“…The literature search identified 83 articles, only 35 were ultimately selected 5–39 . The corresponding results are summarized in Table 2.…”