Impetigo Herpetiformis Unresponsive to Therapy in a Pregnant Adolescent

Arslanpence, Ilhan; Dede, F. Suat; Gökçü, Mehmet; Gelişen, Orhan

doi:10.1016/s1083-3188(03)00040-8

Cited by 35 publications

(40 citation statements)

References 10 publications

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“…There are considerable debates on the classification of IH [2,11,12,17,18]. Some authorities consider the disease as an acute pustular phase of psoriasis, and it may also be a rare form of generalized pustular psoriasis (GPP) in pregnancy.…”

Section: Discussionmentioning

confidence: 99%

“…According to the literature review, the treatments of IH mainly include systemic corticosteroids (prednisone), cyclosporine, antibiotic, methotrexate, ultraviolet A (PUVA), system retinoids and clofazimine [2,7,8,9,10,11,12,17,18,22,23,24]. At the beginning of IH or in mild cases, corticosteroids are usually efficacious at a low dose of 15-30 mg a day.…”

Section: Discussionmentioning

confidence: 99%

“…In some severe cases, it is necessary to increase the dose to 40-60 mg a day to control the symptoms [2,22]. However, some cases reported that the patients were unresponsive to corticosteroid therapy [10,17,22]. In progressive cases, oral cyclosporine is the second-line therapy for IH and antibiotics should be administered to treat or prevent secondary infection [2,9,17,22].…”

Section: Discussionmentioning

confidence: 99%

“…However, some cases reported that the patients were unresponsive to corticosteroid therapy [10,17,22]. In progressive cases, oral cyclosporine is the second-line therapy for IH and antibiotics should be administered to treat or prevent secondary infection [2,9,17,22]. Furthermore, it is reported that taking parenteral calcium, vitamin D, infliximab and pyridoxine in high doses, as well as chorionic gonadotropin, is effective for IH during pregnancy.…”

Section: Discussionmentioning

confidence: 99%

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Impetigo Herpetiformis during Pregnancy: A Case Report and Literature Review

Gao

Yao³

2013

Dermatology

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Background: Impetigo herpetiformis (IH) is a rare pustular dermatosis that typically occurs in pregnant women with unknown etiology. Case Report: We report an 18-year-old primigravida who presented with IH at nearly 30 weeks' gestation and was the first patient reported in mainland China. The patient's condition deteriorated rapidly in spite of treatment with corticosteroids and antibiotics, so we decided to terminate the pregnancy by induction of labor. After vaginal delivery she developed fever and her skin lesions did not disappear naturally. Fortunately her symptoms were resolved with the treatment of antibiotics and acitretin, and at day 60 postpartum her skin lesions had completely disappeared. Conclusion: Although IH is associated with high mortality and morbidity in both fetus and mother, a better prognosis could be achieved with an immediate diagnosis and proper treatment. The etiology of IH needs to be further explored and the process of diagnosis and therapy should be standardized.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Impetigo Herpetiformis during Pregnancy: A Case Report and Literature Review

Gao

Yao³

2013

Dermatology

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“…After healing, the original lesions become encrusted and cause residual brownish pigmentation. In the severest cases, the mucous membranes, such as those of the tongue, mouth and esophagus, may be affected by erosive lesions [2]. Patients with IH often visit clinics with systemic symptoms including fever, sweating, delirium, malaise, diarrhea, vomiting, chills and arthralgia.…”

Section: Discussionmentioning

confidence: 99%

Impetigo Herpetiformis with Gestational Hypertension: A Case Report and Literature Review

et al. 2011

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Background: Impetigo herpetiformis (IH) is a rare skin disorder that occurs during pregnancy. It was previously associated with high maternal and fetal mortality and morbidity, but now has a better prognosis. Case Report: We report a case of a pregnant woman with IH who presented with generalized erythematous pustular eruptions in the 32nd week of gestation. The IH progressed rapidly, and gestational hypertension was observed in the 36th week. The lesions did not subside, despite treatment with corticosteroids and phototherapy. She delivered a healthy male baby via cesarean section in the 37th week. One month after her delivery, her skin returned to normal, except for residual pigmentation, with complete recovery 3 months postpartum. Conclusion: An experienced medical team comprising obstetricians, dermatologists, perinatologists and neonatologists is critical to aggressively treat this life-threatening specific dermatosis of pregnancy and to prevent ensuing complications, such as fluid and electrolyte imbalance, secondary infection and placental insufficiency.

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Cyclosporine Resolves Generalized Pustular Psoriasis of Pregnancy

Kapoor¹,

Kapoor²

2006

Arch Dermatol

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Impetigo Herpetiformis Unresponsive to Therapy in a Pregnant Adolescent

Cited by 35 publications

References 10 publications

Impetigo Herpetiformis during Pregnancy: A Case Report and Literature Review

Impetigo Herpetiformis during Pregnancy: A Case Report and Literature Review

Impetigo Herpetiformis with Gestational Hypertension: A Case Report and Literature Review

Cyclosporine Resolves Generalized Pustular Psoriasis of Pregnancy

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