Impetigo herpetiformis: A variant of pustular psoriasis or a separate entity?

Lotem, M; Katzenelson, Varda; Rotem, Arie; Hod, Moshe; Sandbank, Miriam

doi:10.1016/s0190-9622(89)70042-6

Cited by 73 publications

(64 citation statements)

References 10 publications

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“…20 Unlike pustular psoriasis, these patients often have no personal or family history of psoriasis, and IH does not generally progress to erythroderma. 21 The histopathology is identical to pustular psoriasis, showing subcorneal neutrophils and psoriasiform hyperplasia. Direct immunofluorescence skin testing is negative.…”

Section: Impetigo Herpetiformismentioning

confidence: 86%

“…Most dermatologists classify IH as a subtype of pustular psoriasis, 20 due to its clinical similarity to von Zumbusch type pustular psoriasis, whereas others retain it as a distinct entity. 21 IH is characterized by sterile grouped pustules on the periphery of polycyclic erythematous plaques on the trunk and extremities ( Figure 1). It is often accompanied by systemic symptoms,including fever, nausea, and malaise.…”

Section: Impetigo Herpetiformismentioning

confidence: 99%

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Inflammatory and glandular skin disease in pregnancy

Yang

Teeple

Muglia

et al. 2016

Clinics in Dermatology

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Section: Impetigo Herpetiformismentioning

confidence: 86%

Section: Impetigo Herpetiformismentioning

confidence: 99%

Inflammatory and glandular skin disease in pregnancy

Yang

Teeple

Muglia

et al. 2016

Clinics in Dermatology

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“…Th-1 sitokinler psoriaziste alevlenmeye sebep olmaktadır 9 . Bunun dışında, İH'de hipokalsemi olması ve gebelikte gözlenmesinden dolayı psoriazisten farklı bir hastalık olarak da yorumlanmıştır 3,4 . İH'de birçok tedavi seçeneği bulunmaktadır.…”

Section: Discussionunclassified

“…Birçok yazar, İH'nin püstüler psoriazisin gebelikte endokrin değişikliklerle alevlenen jeneralize formu olduğunu ileri sürmektedir 2 . Bazı yazarlar ise; İH'de hipokalsemi olması ve gebelikte gözlenmesi sebebiyle psoriazisten farklı bir hastalık olarak yorumlamışlardır 3,4 . İmpetigo herpetiformis, genellikle gebeliğin üçüncü trimestrinde ortaya çıkan yaygın püstüllerle karakterizedir.…”

Section: Gi Riflunclassified

Tedaviye Dirençli İmpetigo Herpetiformis'te İntravenöz İmmunglobulin Tedavisinin Etkinliği: Olgu Sunumu

...

2012

Turkderm

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Özetİmpetigo herpetiformis (İH), yüksek fetal morbidite ve mortaliteye sahip, bazen gebeliğin sonlandırılmasını gerektirebilen bir hastalıktır. Etkili olduğu belirtilen farklı tedavi seçenekleri bulunmaktadır. Yirmi üç yaşında, psoriazis öyküsü olan 25 haftalık gebe olgu, ani başlangıçlı jeneralize püstüler döküntülerle başvurdu. Klinik bulgular ve histopatolojik değerlendirme ile İH tanısı konuldu. Sistemik prednizolon (2 mg/kg/gün) üç hafta süreyle uygulandı. Yanıt olmadığı için siklosporin A (3mg/kg/gün) ilave edildi. İki hafta siklosporin A ve sistemik prednizolon kombine kullanılmasına rağmen deri bulguları gerilemedi. Tedavilere ek olarak 30. Sum maryImpetigo herpetiformis (IH), if left untreated, is associated with a high rate of perinatal morbidity and mortality and may lead to the decision of termination of pregnancy. There are various and effective therapeutic agents available for the treatment of the disease. A 23-year-old woman with a history of plaque psoriasis presented with a sudden generalized pustular eruption on the 25th week of her first gestation. The diagnosis was made based on the clinical and histopathological findings. The patient was treated with systemic prednisolone (2 mg/kg/d) first and, cyclosporine A (3 mg/kg/d) was added to the treatment after two weeks because prednisolone was not effective alone. The lesions did not regress despite four weeks of combined treatment with prednisolone and cyclosporine. Intravenous immunoglobuline (IVIG) (0.3 g/kg/d, 6 days) was added on the 30th week of gestation and resulted in regression of cutaneous rashes. On the 33rd week of gestation, IVIG (0.7 g/kg/d, 3 days) was repeated due to reactivation of pustules, and an improvement was observed. In this case report, we called attention to IVIG therapy in IH, for having the pregnancy continued enough for the fetal maturation before the delivery. (Turk derm 2012; 46: 104-6

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“…A skin biopsy performed by a dermatologist confirmed the diagnosis of impetigo herpetiformis Laboratory Data Laboratory investigations performed 1 week prior to pre¬ sentation demonstrated the following values: calci- urn, 1.72 mmol/L (normal, 2.12 to 2.64 mmol/L); phosphate, 0.54 mmol/L (normal, 0.80 to 1.45 mmol/L); albumin, 33 g/L (normal, 35 to 55 g/L); leukocyte count, 12.3 x 107L (normal, 4.0 to 10.5 x 107L), with a differential of 0.88 polymorphonuclear leukocytes, 0.08 lymphocytes, 0.03 band forms, and 0.01 mononuclear cells; hematocrit, 0.34 (normal, 0.36 to 0.48); lactate dehydrogenase, total bilirubin, total protein, serum urea nitrogen, uric acid, and serum glucose, within normal limits; alkaline phosphatase, 197 TJ/L (normal, 30 to 120 U/L) (mildly elevated at initial screening); serum cholesterol, 5,94 mmol/L (normal, <5.85 mmol/L) (mildly elevated at initial screening); and serum cholesterol sulfate, normal.…”

Section: Report Of a Casementioning

confidence: 99%

Impetigo Herpetiformis Associated With Hypocalcemia of Congenital Rickets

Holm¹

1991

Arch Dermatol

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A 30-year-old woman with congenital rickets and autosomal recessive ichthyosis developed impetigo herpetiformis in the second trimester of her first pregnancy. This condition was temporally related to her discontinuation of vitamin D supplements and subsequent hypocalcemia. No associated systemic symptoms were observed, and a healthy baby was delivered prematurely at 34 weeks' gestation. This report supports the association between hypocalcemia and impetigo herpetiformis and raises theoretical questions regarding a relationship between vitamin D metabolism and various epidermal hyperproliferative states.

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Impetigo herpetiformis: A variant of pustular psoriasis or a separate entity?

Cited by 73 publications

References 10 publications

Inflammatory and glandular skin disease in pregnancy

Inflammatory and glandular skin disease in pregnancy

Tedaviye Dirençli İmpetigo Herpetiformis'te İntravenöz İmmunglobulin Tedavisinin Etkinliği: Olgu Sunumu

Impetigo Herpetiformis Associated With Hypocalcemia of Congenital Rickets

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