Impetigo herpetiformis

Abstract

Impetigo herpetiformis is a rare pustular disorder that occurs primarily in pregnancy and is often associated with hypocalcemia. The onset commonly presents in the last trimester of pregnancy; the condition may persist until delivery and it rarely continues in the postpartum period. There is an increase in morbidity and mortality for the mother and the fetus. As a result, immediate diagnosis and treatment is crucial. The purpose of this article is to delineate the clinical picture of this disease, its treatment, and the effect on the mother and the fetus.

Impetigo Herpetiformis with Gestational Hypertension: A Case Report and Literature Review

“…After several weeks, the thick scabs on the other 2 patients dried up and started falling off. However, only 1 patient survived [1]. The other patient died of rapidly progressive disease and associated complications.…”

“…In 1982, Oumeish and Parish [1] treated a patient who presented with recurrent IH; she had used oral contraceptive pills regularly (a combination of ethinyl estradiol and progesterone). This disease appeared in all 9 of the patient’s pregnancies within a 12-year period [1]. In 2005, Chaidemenos et al [6] described the case of a patient with IH who experienced postpartum relapse of the disease.…”

“…Although IH is rare, it is related to increased morbidity and mortality for both the mother and fetus [1]. On searching Medline for the key words ‘impetigo herpetiformis’, we found 117 related articles (1949–2009).…”

Impetigo Herpetiformis during Pregnancy: A Case Report and Literature Review

“…Impetigo herpetiformis (IH), firstly introduced by von Hebra [1] in 1872, is characterized as an acute pustular eruption that mainly occurs in the last trimester of pregnancy with a serious risk to the mother and the fetus [2]. According to the literature, although the causes of impetigo herpetiformis are still unknown [3,4], complications like hypoparathyroidism and hypocalcemia are common in patients [5,6,7,8].…”

“…According to the literature, although the causes of impetigo herpetiformis are still unknown [3,4], complications like hypoparathyroidism and hypocalcemia are common in patients [5,6,7,8]. Generally the patients recovers after delivery, but IH frequently recurs in subsequent pregnancy [2,7,8,9,10]. Early diagnosis and treatment is important in order to get a better prognosis for both the mother and fetus.…”