Impedance Spectroscopy: Applications, Advances and Future Trends

Kanoun, Olfa; Kallel, Ahmed Yahia; Nouri, Hanen; Atitallah, Bilel Ben; Haddad, Dhia; Hu, Zheng; Talbi, Malak; Al‐Hamry, Ammar; Munja, Rohan; Wendler, Frank; Barioul, Rim; Keutel, Thomas; Mangler, Andreas

doi:10.1109/mim.2022.9759355

Cited by 22 publications

(9 citation statements)

References 71 publications

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“…There is a further trend towards the diversification of solutions for measurement and sensor technology. The non-invasiveness of the method and the possibility to track material and system states at relatively low costs also make it attractive for the control and quality improvement of processes in the environment and industry as with health monitoring and sensor applications [9].…”

Section: Future Of Impedance Spectroscopymentioning

confidence: 99%

Impedance Spectroscopy and Its Application in Measurement and Sensor Technology

2022

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Section: Future Of Impedance Spectroscopymentioning

confidence: 99%

Impedance Spectroscopy and Its Application in Measurement and Sensor Technology

2022

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“…However, in BIS measurement based on multisine excitation, measurement of the response signal usually needs to satisfy the Nyquist sampling theorem; that is, the sampling frequency must be at least twice the highest frequency of the excitation signal to ensure that no spectral aliasing occurs [27]. Furthermore, when higher harmonics are generated due to system nonlinearities, higher sampling frequencies are required.…”

Section: Introductionmentioning

confidence: 99%

Bioimpedance spectroscopy measurement method based on multisine excitation and integer-period undersampling

Hong

Zhang

et al. 2023

Meas. Sci. Technol.

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Bioimpedance spectroscopy (BIS) is a detection technology that uses the bioimpedance characteristics and changes law of human tissue to analyze its physiological and pathological states, and is widely used in clinical and scientific research applications. Traditional BIS measurement needs to satisfy the Nyquist sampling theorem, so as to ensure that the measurement signal has no frequency aliasing, but at the same time, the sampling frequency and the number of sampling points will be increased, which will increase the computation and hardware cost. This paper proposes a novel BIS measurement method based on multisine excitation and integer-period undersampling (IPUS) technology. Firstly, the multisine-based IPUS theory was deduced, and the BIS measurement principle based on multisine excitation and IPUS technology was introduced. Secondly, a BIS measurement system based on FPGA+ADC+DAC architecture was designed, and a multisine excitation with 32 pseudo-logarithmically distributed frequency components in the range of 2-997 kHz was generated. The comparative BIS measurement experiments on three RC three-element models were carried out under the Nyquist sampling condition (fs = 2.56 MHz) and under the IPUS condition (fs = 512 kHz), respectively. Experimental results showed that the average amplitude error of BIS measurement under the Nyquist sampling condition is 0.80% (mean) ± 1.19% (std), while the average amplitude error under the IPUS condition is 1.02% (mean) ± 1.13% (std). Moreover, the signal to nosie ratio (SNRz) is calculated in 40 repeated BIS measurements, where the mean SNRz is 63.60dB under IPUS condition, similar to the value of 62.77dB under Nyquist sampling condition. The proposed multisine-based IPUS theory and its implementation method in this paper can complete a BIS measurement with only one fundamental period, and need the sampling frequency and sampling points lower than the requirements of the Nyquist theory, which lay a theoretical and technical foundation for BIS measurement system with reduced hardware requirements and computation cost.

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“…Impedance spectroscopy is an established measurement method for characterizing electrical properties, i.e., complex conductivity and permittivity of materials and systems [ 1 ]. Impedance measurement systems have been developed for a variety of applications, including material characterization with inductive sensors [ 2 ], chemical parameters investigation [ 3 ], and characterization of biological tissues [ 4 , 5 ]. Impedance spectroscopy can be applied to monitor human activity [ 6 ], diagnose muscles [ 7 ], detect and characterize cancer [ 8 ], and monitor human health on a daily basis [ 9 ].…”

Section: Introductionmentioning

confidence: 99%

“…Impedance spectroscopy can be applied to monitor human activity [ 6 ], diagnose muscles [ 7 ], detect and characterize cancer [ 8 ], and monitor human health on a daily basis [ 9 ]. In this case, it is called bioelectrical impedance spectroscopy (BIS) [ 5 ], which is the main focus of this paper. BIS is a non-invasive technique that injects a constant safe current into the biological tissue or human body through a pair of electrodes in a predefined frequency range.…”

Section: Introductionmentioning

confidence: 99%

Comparative Study of Measurement Methods for Embedded Bioimpedance Spectroscopy Systems

Atitallah

Kallel

Bouchaala

et al. 2022

Sensors

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Bioimpedance spectroscopy (BIS) is an advanced measurement method for providing information on impedance changes at several frequencies by injecting a low current into a device under test and analyzing the response voltage. Several methods have been elaborated for BIS measurement, calculating impedance with a gain phase detector (GPD), IQ demodulation, and fast Fourier transform (FFT). Although the measurement method has a big influence on the measurement system performance, a systematical comparative study has not been performed yet. In this paper, we compare them based on simulations and experimental studies. To maintain similar conditions in the implementation of all methods, we use the same signal generator followed by a voltage-controlled current source (VCCS) as a signal generator. For performance analysis, three DUTs have been designed to imitate the typical behavior of biological tissues. A laboratory impedance analyzer is used as a reference. The comparison addresses magnitude measurement accuracy, phase measurement accuracy, signal processing, hardware complexity, and power consumption. The result shows that the FFT-based system excels with high accuracy for amplitude and phase measurement while providing the lowest hardware complexity, and power consumption, but it needs a much higher software complexity.

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Impedance Spectroscopy: Applications, Advances and Future Trends

Cited by 22 publications

References 71 publications

Impedance Spectroscopy and Its Application in Measurement and Sensor Technology

Impedance Spectroscopy and Its Application in Measurement and Sensor Technology

Bioimpedance spectroscopy measurement method based on multisine excitation and integer-period undersampling

Comparative Study of Measurement Methods for Embedded Bioimpedance Spectroscopy Systems

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