Impedance characteristics of normal oesophageal motor function

Nguyen, H N; Domingues, Gerson R; Winograd, Ron; Koppitz, P.; Lammert, Frank; Silny, Jiri; Matern, Siegfried

doi:10.1097/00042737-200307000-00009

Cited by 13 publications

(16 citation statements)

References 31 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…These values were later confirmed by a Dutch-Australian multicenter study in 42 healthy volunteers using combined water-perfused manometry-impedance systems [9]. A third set of normal data for combined impedance-manometry testing was reported by Nguyen et al in a group of 25 healthy subjects [10]. Bolus transit parameters were similar to prior studies albeit using yoghurt as semisolid test substance.…”

Section: Esophageal Function Testing Using Combined Impedance-manometrysupporting

confidence: 58%

Impedance technology for the management of esophageal disorders

Tutuian

2008

Eur Surg

View full text Add to dashboard Cite

Zusammenfassung. Grundlagen: Impedanzmessungen im Ö sophagus werden zunehmend häufiger zur Erkennung und Quantifizierung der Präsenz von Flüssigkeiten in der Speiseröhren eingesetzt.Methodik: Ü bersicht der klinischen Anwendungen von Impedanzmessungen, insbesondere kombinierte Impedanz-Manometrie und Impedanz-pH-Metrie.Ergebnisse: Kombinierte Impedanz-Manometrie ermöglicht die Quantifizierung des Bolustransites und klärt, inwiefern ösophageale Motilitätsabnormalitäten von einer Bolustransitstörung begleitet sind. Dies ist von besonderem Interesse für Patienten mit nicht-obstruktiver (i.e. funktioneller) Dysphagie und Patienten mit post-operativer Dysphagie.Kombinierte Impedanz-pH-Metrie identifiziert Refluxepisoden unabhängig vom Säuregehalt (i.e. pH). Dieses ist wichtig fü r Patienten mit persistierenden Beschwerden trotz säurehemmender Therapie. Die Möglichkeit Refluxepisoden mit pH > 4 zu identifizieren, bringt neue Fragen betreffend der optimalen Therapie fü r Patienten mit symptomatischem nicht-saurem Reflux.Schlussfolgerungen: Impedanzmessungen ermög-lichen uns Flü ssigkeitsbewegungen in der Speiseröhre zu identifizieren. Die klinische Wertigkeit dieser zusätz-lichen Information dü rfte durch zukü nftige Studien geklärt werden.Schlüsselwörter: Ö sophagusmanometrie, ösophageale pH-Metrie, Impedanzmessungen, kombinierte Impedanz-Manometrie, kombinierte Impedanz-pH-Metrie.Summary. Background: Esophageal impedance measurements are increasingly used to identify and quantify the presence of fluids in the esophagus.Method: A review of the available literature on clinical applications of impedance including combined impedance-manometry testing and combined impedance-pH monitoring is done.Results: Combined impedance-manometry testing offers the opportunity to quantify esophageal bolus transit and clarifies the implications of esophageal motility abnormalities on esophageal function. This is of particular interest in patients with non-obstructive dysphagia and in patients with post-fundoplication dysphagia.Combined impedance-pH monitoring allows the detection of gastroesophageal reflux episodes independent of pH. This is of particular importance when evaluating patients with persistent symptoms on acid suppressive therapy. The ability to detect gastroesophageal reflux episodes with pH> 4 unfolds new questions on the optimal approach to patients with symptomatic nonacid reflux.Conclusions: Impedance technology allows the detection of fluid movements in the esophagus; further studies will determine the clinical utility of this new information.

show abstract

Section: Esophageal Function Testing Using Combined Impedance-manometrysupporting

confidence: 58%

Impedance technology for the management of esophageal disorders

Tutuian

2008

Eur Surg

View full text Add to dashboard Cite

show abstract

“…Their results revealed that total bolus transit time for both liquid and viscous swallows were 12.5 s and greater than 90% of individuals had > 80% of the liquid swallows associated with complete bolus transit and > 70% of the viscous swallows associated with complete bolus transit [10] . Two other studies in normal controls revealed similar bolus transit parameters and thus, it appears that this technology is reproducible in normal subjects [11,12] .…”

Section: Mii: Clinical Aspectssupporting

confidence: 56%

New technologies in the gastrointestinal clinic and research: Impedance and high-resolution manometry

Pandolfino¹,

Kahrilas²

2009

WJG

View full text Add to dashboard Cite

“…Fig. 2 Simultaneous tracing of impedance (CH) and pressure (P) in a healthy volunteer [13,16]. A brief spike and decrease of impedance (CH1) with increase of pressure (P1) is observed at the level of the ring sphincter system of the upper esophageal sphincter.…”

Section: Impedance Manometry In Healthy Human Subjectsmentioning

confidence: 99%

“…The increase in pressure (P1-P3) which opens the lumen produces a peristaltic wave as the wall tension rises and correlates with an axial lengthening of the esophagus. This mechanism may explain why a correlation between bolus transit time and pressure amplitude cannot be established in impedance manometry measurements [16]. This relationship would be expected if the propulsion occurred by contraction of a series of circular muscle elements.…”

Section: Impedance Manometry In Healthy Human Subjectsmentioning

confidence: 99%