Impedance-Based Detection of Tissue Using a Multi-Electrode Device

Measuring Impedance of Tissues Using a Microfabricated Microelectrode Array

“…It was shown by Stante (2009) et al that it is possible to differentiate between healthy skin and melanoma tissue using EIS between two electrodes. The success of Stante"s work led to the next step which was the development of an array of electrodes to see if it could be used as a technique to create an electrical image of the tissue [12,13]. Impedance spectroscopy is an important tool, but there needs to be an understanding of other detection methods currently being researched and juxtaposing it with impedance spectroscopy.…”

“…This implicated the ability to use multiple frequencies ranges to more accurately detect melanoma while as in Glickman (2004) measure the impedance differences between electrodes for melanoma vs. healthy skin tissue [12,13]. Using wires can distort the image because the impedance gets integrated over the size of the sensor resulting in an averaged impedance value in that area.…”

“…Using a similar concept as State and Fleshmen et al [12,13]. Resistors were placed between the electrodes to see how accurately the MEA was able to measure resistances across the electrode.…”