Impairment of voluntary saccades and facilitation of reflexive saccades do not co-occur in Parkinson’s disease

Stockum, Saskia van; MacAskill, Michael R.; Anderson, Tim

doi:10.1016/j.jocn.2011.10.014

Cited by 22 publications

(27 citation statements)

References 28 publications

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“…Van Stockum and coworkers indicated that impairment of voluntary saccades in PD does not happen with reflexive saccade facilitation. [53] PD patients who elicit reflexive saccades at shorter latencies perform similar to control subjects on voluntary saccade task suggesting that PD affects latencies, which is independent of the type of saccadic eye movements. PD patients were hypometric overall and latencies did not correlate with these hypometric saccades.…”

Section: Saccadic Eye Movements In Parkinson's Diseasementioning

confidence: 99%

Saccadic eye movements in Parkinson′s disease

Srivastava

Sharma

et al. 2014

Indian J Ophthalmol

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This review focuses on saccadic eye movement research in Parkinson's disease (PD) patients. Results from various studies related to Parkinson disease and saccades have been discussed in terms of various saccadic parameters like latency, amplitude, velocity and gain. Neural circuitry of saccadic eye movements and cognitive processes and it's relation with altered saccadic performance in Parkinson disease has been discussed here. This article also covers various research paradigms commonly used to study saccades. Effects of medication on saccadic parameters in PD patients have also been discussed along with the effects of deep brain stimulation of subthalamic nucleus on saccadic performance in PD patients. Literature review was done using online Pubmed search engine and National Medical Library.

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Section: Saccadic Eye Movements In Parkinson's Diseasementioning

confidence: 99%

Saccadic eye movements in Parkinson′s disease

Srivastava

Sharma

et al. 2014

Indian J Ophthalmol

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“…Cognitive processes underpin VS during real-world activities, as reflexive activity which is not governed by top-down cognitive control is rare during such situations (Anderson and MacAskill, 2013). Cognitive deficits (visuospatial, attentional and memory domains) influence VS in PD and older adults (van Stockum et al, 2008, van Stockum et al, 2012, van Stockum et al, 2011, van Stockum et al, 2013).…”

Section: Interpretation Of Outcomesmentioning

confidence: 99%

“…Investigation into VS during real-world activity in PD is warranted, to further clarify the links between these motor, cognitive and visual impairments. Eye-tracking technology has been used to further understand the visual strategies of PD subjects since the 1960's (Terao et al, 2011, van Stockum et al, 2012, demonstrating VS impairments, such as hypometric voluntary (van Stockum et al, 2012, Anderson and and variable reflexive (Chambers and Prescott, 2010) saccades. However until recently most research using eye-trackers involved small sample sizes (Anderson and MacAskill, 2013).…”

Section: Introductionmentioning

confidence: 99%

The measurement of visual sampling during real-world activity in Parkinson's disease and healthy controls: A structured literature review

Stuart

Alcock

Galna

et al. 2014

Journal of Neuroscience Methods

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“…Parkinson's disease (D'Ostilio, Cremers, Delvaux, Sadzot, & Garraux, 2013;van Stockum, MacAskill, & Anderson, 2012;van Stockum, MacAskill, Myall, & Anderson, 2013;Vervoort et al, 2013), Huntington's disease (Patel, Jankovic, Hood, Jeter, & Sereno, 2012), autism (Vernazza-Martin, Longuet, Chamot, & Orève, 2013) and mild traumatic brain injury (Zhang, Red, Lin, Patel, & Sereno, 2013).…”

Section: Understanding Automaticity and Volitionmentioning

confidence: 99%

Saccade-like behavior in the fast-phases of optokinetic nystagmus: An illustration of the emergence of volitional actions from automatic reflexes.

Harrison

Freeman

Sumner

2014

Journal of Experimental Psychology: General

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As a potential exemplar for understanding how volitional actions emerged from reflexes, we studied the relationship between an ancient reflexive gaze stabilisation mechanism (optokinetic nystagmus) and purposeful eye movements (saccades) that target an object.Traditionally these have been considered distinct (except in the kinematics of their execution) and studied independently. We find that the fast-phases of optokinetic nystagmus (OKN) clearly show properties associated with saccade planning: (1) They are characteristically delayed by irrelevant distractors in an indistinguishable way to saccades (the saccadic inhibition effect); (2) horizontal OKN fast-phases produce curvature in vertical targeting saccades, just like a competing saccade plan. Thus we argue that the saccade planning network plays a role in the production of OKN fast-phases, and question the need for a strict distinction between eye movements that appear to be automatic or volitional. We discuss whether our understanding might benefit from shifting perspective and considering the entire 'saccade' system to have developed from an increasingly sophisticated OKN system.

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Impairment of voluntary saccades and facilitation of reflexive saccades do not co-occur in Parkinson’s disease

Cited by 22 publications

References 28 publications

Saccadic eye movements in Parkinson′s disease

Saccadic eye movements in Parkinson′s disease

The measurement of visual sampling during real-world activity in Parkinson's disease and healthy controls: A structured literature review

Saccade-like behavior in the fast-phases of optokinetic nystagmus: An illustration of the emergence of volitional actions from automatic reflexes.

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