Impairment of visuospatial memory is associated with decreased slow wave sleep in schizophrenia

Göder, Robert; Boigs, Margret; Braun, Sisko; Friege, Lars; Fritzer, Gunther; Aldenhoff, Josef B.; Hinze-Selch, D.

doi:10.1016/j.jpsychires.2004.04.005

Cited by 101 publications

(62 citation statements)

References 54 publications

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“…In a study providing age-appropriated norms for performance in the Rey figure test the differences between the age ranges relevant for our study were significant but small [32] . Earlier studies emphasized the importance of SWS in the consolidation of declarative memory in young healthy subjects or patients with schizophrenia [33,34] . However, there are also several indications of a role of REM sleep in declarative memory processes consistent with the results of our study on depressed patients [35][36][37][38] .…”

Section: Discussionmentioning

confidence: 99%

Sleep in Major Depression: Relation to Memory Performance and Outcome after Interpersonal Psychotherapy

Göder¹,

Fritzer²,

Hinze-Selch³

et al. 2007

Neuropsychobiology

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Background: Earlier findings suggest both a link between sleep and memory consolidation and a relationship between abnormal sleep at baseline and poor treatment outcome in major depression after interpersonal psychotherapy (IPT). Methods: Pre-treatment polysomnography was examined in 32 patients with a major depressive episode (mean age = 39.5 years, 20 women). Declarative memory was tested by the Rey-Osterrieth Complex Figure Test and a paired associative word list and procedural learning was assessed by a mirror tracing skill. All patients were treated with IPT according to the manual and did not receive any antidepressant medication. Twenty-three patients took part in a minimum of 12 sessions of IPT. Remission was defined as 2 consecutive weeks with a score <8 on the Hamilton Rating Scale of Depression. Results: Declarative visual memory performance was associated with total sleep time and total amount of rapid eye movement sleep. In IPT remitters (n = 14), there was a trend towards a decrease in rapid eye movement density (first period) and a significant decrease in delta power in pre-treatment sleep in comparison to non-remitters (n = 9). Treatment outcome after IPT was also associated with declarative memory performance at baseline (as a trend). Conclusions: Further indications of a role of sleep in memory processes and of the importance of specific sleep parameters as markers for a positive treatment response to psychotherapy were found.

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Section: Discussionmentioning

confidence: 99%

Sleep in Major Depression: Relation to Memory Performance and Outcome after Interpersonal Psychotherapy

Göder¹,

Fritzer²,

Hinze-Selch³

et al. 2007

Neuropsychobiology

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“…Forest and coworkers [42] demonstrated a negative correlation between the amount of stage 4 sleep and reaction time in a selective attention task. A third study by Gö der and coworkers [43] found that SWS deficits and impaired SE correlated significantly with impaired performance on a test of declarative memory.…”

Section: Clinical and Neuropsychologic Correlations Clinical Correlatesmentioning

confidence: 95%

Sleep in Schizophrenia: Impairments, Correlates, and Treatment

Benson¹

2006

Psychiatric Clinics of North America

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“…These results support previous findings, which indicated that visual memory deficits in patients with schizophrenia are characterized by both organizational processing impairments and retention difficulties 4 or problems during consolidation. 7 We found that patients with schizophrenia lost more information than controls between the immediate recall condition and the delayed recall condition, indicating possible retention and/or retrieval deficits.…”

Section: Discussionmentioning

confidence: 62%

“…4 These studies have consistently reported that patients with schizophrenia are deficient in visual memory, 5,6 but the mechanisms underlying this deficit are poorly understood. 4,5 Some researchers have reported that non-verbal memory deficit is associated with problems related to consolidation, 7 and others have suggested that visual memory impairment is associated with a deficit related to organization and encoding, 6 or with a combined deficit in organization and retention. 4 Glahn et al recently examined non-verbal memory impairment in patients with schizophrenia and found that they performed worse than patients with bipolar disorder or normal controls, but observed differential impairment only when organizational demands were significant.…”

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confidence: 99%

Effect of organizational strategy on visual memory in patients with schizophrenia

Kim

Namgoong

Youn

2008

Psychiatry Clin Neurosci

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Aims: The aim of the present study was to examine how copy organization mediated immediate recall among patients with schizophrenia using the Rey–Osterrieth Complex Figure Test (ROCF).Methods: The Boston Qualitative Scoring System (BQSS) was applied for qualitative and quantitative analyses of ROCF performances. Subjects included 20 patients with schizophrenia and 20 age‐ and gender‐matched healthy controls.Results: During the copy condition, the schizophrenia group and the control group differed in fragmentation; during the immediate recall condition, the two groups differed in configural presence and planning; and during the delayed recall condition, they differed in several qualitative measurements, including configural presence, cluster presence/placement, detail presence/placement, fragmentation, planning, and neatness. The two groups also differed in several quantitative measurements, including immediate presence and accuracy, immediate retention, delayed retention, and organization. Although organizational strategies used during the copy condition mediated the difference between the two groups during the immediate recall condition, group also had a significant direct effect on immediate recall.Conclusion: Schizophrenia patients are deficient in visual memory, and a piecemeal approach to the figure and organizational deficit seem to be related to the visual memory deficit. But schizophrenia patients also appeared to have some memory problems, including retention and/or retrieval deficits.

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Impairment of visuospatial memory is associated with decreased slow wave sleep in schizophrenia

Cited by 101 publications

References 54 publications

Sleep in Major Depression: Relation to Memory Performance and Outcome after Interpersonal Psychotherapy

Sleep in Major Depression: Relation to Memory Performance and Outcome after Interpersonal Psychotherapy

Sleep in Schizophrenia: Impairments, Correlates, and Treatment

Effect of organizational strategy on visual memory in patients with schizophrenia

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