Impaired quality of life and sexual function in overweight and obese men: the European Male Ageing Study

Han, Thang S.; Tajar, Abdelouahid; O’Neill, Terence W; Jiang, Min; Bártfai, György; Boonen, Steven; Casanueva, Felipe F.; Finn, Joseph D.; Forti, Gianni; Giwercman, Aleksander; Huhtaniemi, Ilpo; Kula, Krzysztof; Pendleton, Neil; Punab, Margus; Silman, Alan J.; Vanderschueren, Dirk; Lean, Michael E. J.; Wu, Frederick C. W.; _, _

doi:10.1530/eje-10-1129

Cited by 94 publications

(65 citation statements)

References 39 publications

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“…International Index of Erectile Function (IIEF). The IIEF is a widely-used, 15-item scale that assesses 5 domains of male sexual functioning: erectile function (range: 0-30); orgasmic function (0-10); sexual desire (2-10); intercourse satisfaction (0-15); and overall satisfaction (2)(3)(4)(5)(6)(7)(8)(9)(10). Lower scores indicate less satisfaction and greater dysfunction [30,31].…”

Section: Methodsmentioning

confidence: 99%

“…A large number of studies have found a relationship between extreme obesity and impairments in quality of life, as well as greater depressive symptoms and increased body image dissatisfaction [3][4][5][6][7]. Individuals with obesity often report untoward changes in sexual functioning and decreased sexual satisfaction [6,[8][9][10][11][12][13]. In a recent study of individuals with extreme obesity who presented for bariatric surgery, 51% of women and 36% of men reported a sexual dysfunction [13].…”

mentioning

confidence: 99%

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Sexual functioning and sex hormones in men who underwent bariatric surgery

Sarwer

Spitzer

Wadden

et al. 2015

Surgery for Obesity and Related Diseases

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Men who lost approximately one third of their weight after Roux-en-Y gastric bypass experienced significant increases in total testosterone and SHBG. They did not, however, report significant improvements in sexual functioning, relationship satisfaction, or mental health domains of HRQoL. This pattern of results differs from that of women who have undergone bariatric surgery, who reported almost uniform improvements in sexual functioning and psychosocial status.

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Section: Methodsmentioning

confidence: 99%

mentioning

confidence: 99%

Sexual functioning and sex hormones in men who underwent bariatric surgery

Sarwer

Spitzer

Wadden

et al. 2015

Surgery for Obesity and Related Diseases

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“…Physical activity and a low-calorie diet allow weight loss, self-image improvement and better quality of life, as well as better sexual function and satisfaction [47][48][49][50]. There is, however, limited data as to whether reduction in body weight by itself would improve sexual function.…”

Section: Sexual Fantasiesmentioning

confidence: 99%

Zależność pomiędzy funkcją seksualną a wskaźnikiem masy ciała i stężeniem hormonów steroidowych u młodych mężczyzn

Jastrzebska¹,

Walczak-Jędrzejowska²,

Kramek³

et al. 2014

Endokrynologia Polska

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Introduction: In older men, sexual disorders may be the result of a decrease in testosterone and an increase in sex hormone binding globulin (SHBG) serum levels. Although obesity may enhance the decline of testosterone, it is also the cause of metabolic disorders, which are additional risk factors of erectile dysfunction. The purpose of this study was to investigate whether elevated body weight is associated with decreased serum testosterone concentrations and reduced sexual function in young men. Material and methods: Data on general health, medication, depressive symptomatology and sexual life was obtained from 136 men aged 20-49 years. Blood levels of LH, total testosterone (TT), dehydroepiandrosterone sulfate (DHEA-S), oestradiol, SHBG, total cholesterol, LDL-and HDL-cholesterol, and triglycerides were determined. Body mass index (BMI), waist to hip ratio (WHR) and free testosterone index (FTI) were calculated. Results: A significantly reduced occurrence of sexual fantasies, morning erections and erectile function scores was observed in the oldest group compared to the youngest men with normal BMI, although orgasmic function was unchanged. A significant decrease in TT serum levels was observed in obese 30-year-olds compared to men with normal BMI, while in obese 40-year-olds decreased LH and SHBG levels were also found. No differences in the levels of lipids and sexual achievements were found among men with different BMI. However, erectile function and morning erections significantly negatively correlated with age, BMI and WHR, and positively with FTI, but not with other studied hormones and lipids.

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“…However, the cross-sectional association between low T and symptoms was attenuated after adjusting for body mass index (BMI) and comorbidities (5), underlining the multicausal origin of putative symptoms of hypogonadism in ageing men. Moreover, obesity, independent of T, is associated with sexual (9) and psychological symptoms (10) as well as impaired physical activity (11). Confirming the appearance of these symptoms with the development of biochemical hypogonadism and/or their resolution following recovery to eugonadism (EUG) would support their relevance as specific clinical markers of androgen deficiency, important in the diagnostic workup of men with low T.…”

mentioning

confidence: 99%