Abstract:Glucose‐6‐phosphate dehydrogenase (G6PD) provides reducing power to all cells in the form of NADPH to meet the cellular needs for reductive biosynthesis and maintenance of the cellular redox homeostasis. We have previously reported that G6PD‐deficient cells suffer high oxidative stress and these cells are more susceptible to viral infection than normal counterparts. However, how G6PD deficiency may affect cellular signaling remains elusive. Toward this end, we determined the effects of G6PD status on inflammat… Show more
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.