2002
DOI: 10.1176/appi.ajp.159.4.546
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Impaired Cortical Network for Preattentive Detection of Change in Speech Sounds in Schizophrenia: A High-Resolution Event-Related Potential Study

Abstract: These results demonstrate impaired frontotemporal cortical networks for preattentive detection of change in speech sounds in schizophrenia. The language-related dysfunction in schizophrenia may be present at the early stage of auditory processing of relatively simple stimuli, such as phonemes, and not just at stages involving higher-order semantic processes.

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Cited by 99 publications
(64 citation statements)
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References 26 publications
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“…This training approach is based on evidence that schizophrenia is characterized by widespread disturbances in frontotemporal neural systems subserving auditory processing and verbal memory. 22,23 Exercises continuously adjust difficulty level to maintain an 80%-85% correct performance rate in order to engage the user in a dense reward schedule and drive successful learning. Correct trials are rewarded with points and animations.…”
Section: Cognitive Training Program and Cg Control Conditionmentioning
confidence: 99%
“…This training approach is based on evidence that schizophrenia is characterized by widespread disturbances in frontotemporal neural systems subserving auditory processing and verbal memory. 22,23 Exercises continuously adjust difficulty level to maintain an 80%-85% correct performance rate in order to engage the user in a dense reward schedule and drive successful learning. Correct trials are rewarded with points and animations.…”
Section: Cognitive Training Program and Cg Control Conditionmentioning
confidence: 99%
“…This training approach is based on evidence that schizophrenia is characterized by widespread disturbances in fronto-temporal neural systems subserving auditory processing and verbal memory. 20,21 Exercises continuously adjust difficulty level to maintain an 80%-85% correct performance rate in order to engage the user in a dense reward schedule and drive successful learning. Correct trials are rewarded with points and animations.…”
Section: Cognitive Training Intervention and Cg Control Conditionmentioning
confidence: 99%
“…Information processing in the brain is reported to be rapid and efficient, without excessive loading on the cerebrum, and divided into automatic processing and attention processing for behavior decision-making (29,30). In general, the former, in which input information is reconciled with images formed by knowledge and memory in the brain, is considered to precede the latter; if mismatching with images occurs, the information is subject to attention processing.…”
Section: Discussionmentioning
confidence: 99%