Impaired Carbohydrate Metabolism in Metabolic Disorders

Biochemical Profiling of Arsenic Trioxide-Induced Impaired Carbohydrate Metabolism and its Therapeutic Intervention via Modulation of Metabolic Pathways

“…Risk factors associated with T2DM are older age, physical inactivity, life stress, obesity, genetic predisposition, central adiposity, family history, medications, some viral or bacterial infections and environmental toxicants. Various epidemiological studies have shown that the chronic exposure of iAs can also cause T2DM (Kulshrestha et al, 2014;Longnecker and Daniels, 2001;Navas-Acien et al, 2006;Sharif et al, 2021;Tseng et al, 2002). According to American Diabetes Association, arsenic-induced DM is classified under the other specific types of diabetes but based on clinical manifestations, the pathophysiology of arsenic-induced DM is similar to that of T2DM (Association, 2004;Paul et al, 2007).…”