Abstract:We aimed to examine the associations of the genotypes for mir146a and mir196a with bladder cancer (BLCA) risk in Taiwan. Mir146a rs2910164 and mir196a rs11614913 genotypes among 375 bladder cancer patients and 375 healthy subjects were determined using the typical PCR-RFLP methodology, and their associations and interactions with age, gender, smoking and alcohol drinking status on BLCA risk were evaluated. Simultaneously, the serum expression level of mir146a was measured using quantitative RT-PCR. The results… Show more
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