Impacts of exercise intervention on various diseases in rats

Wang, Ruwen; Tian, Haili; Guo, Dandan; Tian, Qianqian; Yao, Ting; Kong, Xingxing

doi:10.1016/j.jshs.2019.09.008

Cited by 67 publications

(42 citation statements)

References 171 publications

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“…Balance dysfunction is the main reason for the increase in individuals' disability rates with PD and the decreased health-related quality of life and survival ( 51 ). Many exercise methods are designed to improve the balance ability of persons with PD ( 52 , 53 ). Studies have shown that Tai Chi combines continuous and complex movements naturally, moves slowly to control multi-directional movement, and controls the COG by moving the bodyweight to focus on the control of dynamic postures ( 24 ).…”

Section: Discussionmentioning

confidence: 99%

“…Furthermore, it increases walking speed, reduces the frequency of falls, and effectively improves the patient's gait and balance function ( 55 ). Henceforth, scientific physical exercise is of great benefit to persons with PD, which can help improve the balance ability, reduce the risk of falls, and improve the quality of life ( 52 , 56 , 57 ). However, due to the limitation of time and geographical factors, the participation of persons with PD in rehabilitation training is not high.…”

Section: Discussionmentioning

confidence: 99%

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A Mobile Phone App-Based Tai Chi Training in Parkinson's Disease: Protocol for a Randomized Controlled Study

et al. 2021

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Introduction: With an increasing number of China's aging population, Parkinson's disease (PD) increases year by year. Persons with PD exhibit abnormal balance functions, leading to motor skills difficulties, such as unstable walking or even falling. Therefore, activities of daily living and quality of life are affected. This study aims to explore the effectiveness of Tai Chi training based on the mobile phone app in improving the balance ability of persons with PD.Methods and Analysis: A randomized, single-blind, parallel controlled trial will be conducted in this study. One hundred forty-four persons with PD who meet the inclusion criteria will be randomly divided into a 1:1:1 ratio: (1) control group, (2) basic experimental group (basic app with no Tai Chi training features), and (3) balanced-enhanced experimental group (basic app with Tai Chi training features). Individuals with PD will be evaluated on balance and motor function outcomes. The primary outcome measure is the limits of stability (including the maximum excursion and direction control); the secondary outcome measures include the Unified Parkinson's Disease Rating Scale III (UPDRS-III), Berg Balance Scale (BBS), Functional Reach Test (FRT), Timed Up & Go (TUG), 6-Minute Walk Test (6MWT), and 39-item Parkinson's Disease Questionnaire (PDQ-39). Each group of patients will go through an assessment at baseline, 17 and 33 weeks.Discussion: This study will evaluate the effectiveness of the mobile phone app Tai Chi training on the balance function of persons with PD. We assume that a challenging Tai Chi project based on a mobile phone app will improve balance in the short and long term. As walking stability progresses, it is expected that daily activities and quality of life improve. These findings will be used to improve the effectiveness of future home management measures for persons with PD.Ethics and Dissemination: This study has been approved by the ethical review committee of the Shanghai University of Sport (approval number: 102772019RT056). Informed consent will be obtained from all participants or their guardians. The authors intend to submit the study findings to peer-reviewed journals or academic conferences to be published.Clinical Trial Registration: Chinese Clinical Trial Registry (ChiCTR2000029135).

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

A Mobile Phone App-Based Tai Chi Training in Parkinson's Disease: Protocol for a Randomized Controlled Study

et al. 2021

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“…Pain is a frequent complication of spinal cord injury (SCI), and approximately half to two-thirds of patients with SCI suffer from pain; pain after SCI is typically chronic and neuropathic [1][2][3]. The male-to-female ratio of SCI is high.…”

Section: Introductionmentioning

confidence: 99%

Bibliometric Study of Pain after Spinal Cord Injury

Wang

2021

Neural Plasticity

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Background. The prevalence of comorbid pain after spinal cord injury (SCI) is relatively high in clinical observations and has continued to increase over time. Neuropathic pain (70.14%) is the most popular subject in academic journals after SCI. However, studies that used the bibliometric method to analyze comorbid pain after SCI are still lacking. This study is aimed at combining and integrating acquired information to analyze the global trends of research on the comorbidity of pain after SCI in the last three decades (1990–2019). Methods. Systematic works of literature published from 1990 to 2019 were obtained from the Web of Science Core Collection. CiteSpace software was used to analyze the relationship of publication year with the country, institution, journals, authors, references, and keywords. The regression analysis is used to evaluate the percentage of the category increase or decrease over time significantly. IBM SPSS Statistics was used in the statistical analysis. Results. A total of 730 publications were included in the analysis. A remarkable increase in the number of publications was observed in the study period ( P < 0.05 ). A total of 202 academic journals focused on the categories of clinical neurology, neurosciences, and rehabilitation, and the annual growth rate of articles in these three categories was statistically significant ( P < 0.05 ). The USA (356, 48.77%) and the University of Miami (64, 8.77%) were the country and institution with the highest number of publications, respectively. Spinal Cord, which was the main journal for research on pain after SCI, had the most publications (88, 12.05%). Burst keywords showed that the individual, inflammation, and central sensitization with pain after SCI are the research development trends and focus in this research field. Conclusions. Overall, this study provides the latest research direction for pain after SCI. This historical overview of research into pain after SCI will be a useful basis for further research into development trends, focus issues, cooperators, and cooperative institutions.

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“…Animal research with voluntary or forced exercise reporting the positive impact of physical activity in health is skyrocketing (13)(14)(15)(16)(17). Forced treadmill and wheel exercise, but not voluntary, are the preferred modalities to develop the same training in all animals.…”

Section: Introductionmentioning

confidence: 99%

A Handful of Details to Ensure the Experimental Reproducibility on the FORCED Running Wheel in Rodents: A Systematic Review

et al. 2021

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A well-documented method and experimental design are essential to ensure the reproducibility and reliability in animal research. Experimental studies using exercise programs in animal models have experienced an exponential increase in the last decades. Complete reporting of forced wheel and treadmill exercise protocols would help to ensure the reproducibility of training programs. However, forced exercise programs are characterized by a poorly detailed methodology. Also, current guidelines do not cover the minimum data that must be included in published works to reproduce training programs. For this reason, we have carried out a systematic review to determine the reproducibility of training programs and experimental designs of published research in rodents using a forced wheel system. Having determined that most of the studies were not detailed enough to be reproducible, we have suggested guidelines for animal research using FORCED exercise wheels, which could also be applicable to any form of forced exercise.

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Impacts of exercise intervention on various diseases in rats

Cited by 67 publications

References 171 publications

A Mobile Phone App-Based Tai Chi Training in Parkinson's Disease: Protocol for a Randomized Controlled Study

A Mobile Phone App-Based Tai Chi Training in Parkinson's Disease: Protocol for a Randomized Controlled Study

Bibliometric Study of Pain after Spinal Cord Injury

A Handful of Details to Ensure the Experimental Reproducibility on the FORCED Running Wheel in Rodents: A Systematic Review

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