Impacts of a glyphosate-based herbicide on the gut microbiome of three earthworm species (Alma millsoni, Eudrilus eugeniae and Libyodrilus violaceus): A pilot study

Abstract

Graphical abstract

Pesticides: formulants, distribution pathways and effects on human health – a review

“…Studies have been conducted on representatives of various taxonomic groups. Direct or indirect effects of administration of pesticide formulations on the gut microbiome were mainly detected in rats and mice, but there are data on the effects of pesticides on the gut microbiome of worms [ 175 ], pigs [ 176 ], fish [ 177 ], and honey bees. For example, glyphosate affects susceptibility of the gut microbiome of honey bees to pathogens, making them more vulnerable to infections [ 178 ].…”

Native microbiomes in danger: Could One Health help to cope with this threat to global health?

“…Moreover, it has been shown that the ubiquitous presence of this herbicide in different ecosystems, such as rivers, induces a significant decrease in bacterial richness and diversity [44]. A significant impact on bacterial species loss by glyphosate has even been found in the earthworm microbiome [45].…”

Updating the European Union’s regulation on classification, labelling and packaging of substances and mixtures (CLP): A key opportunity for consumers, workers and stakeholders with interests in the legislation and toxicology of hazardous chemicals

“…For example, more and more studies show that in some particular cases, (e.g. glyphosate and glyphosate-based herbicides) commercial formulations that contain an active compound along with other considered inert ingredients can be more toxic compared with the active compound alone that is used for classification [ [25] , [26] , [27] ]. In addition, hazards not properly described under CLP are constantly being identified, as for example cardiotoxicity, with considerable latency in manifesting adverse effects that bear a long-lasting risk to public health [ [28] , [29] , [30] ].…”